Pediatric obesity and its effects on asthma control
1The Allergy & Asthma Center, Fort Wayne, Indiana.
Insights
This study found no significant difference in asthma control metrics between normal weight, overweight, and obese children. However, overweight children showed a higher mean FEV1% (forced expiratory volume in 1 second), indicating better lung function in this specific measure.
Area of Science:
- Pediatric Pulmonology
- Obesity Research
- Asthma Management
Background:
- Persistent asthma affects many children, with weight being a potential influencing factor.
- Clinical observations suggest obese children may report more asthma symptoms.
- Objective measures of asthma control in relation to weight are crucial for understanding disease management.
Purpose of the Study:
- To investigate the association between overweight/obesity and asthma control in pediatric patients (ages 7-18).
- To compare asthma control parameters across normal weight, overweight, and obese children with persistent asthma.
- To determine if weight status impacts objective measures of lung function and medication use.
Main Methods:
- Retrospective analysis of patient charts from an asthma specialty practice.
- Inclusion criteria: pediatric patients (7-18 years) with persistent asthma.
- Comparison of four variables: controller medications, systemic corticosteroids, FEV1% predicted, and FEV1/FVC% predicted across weight groups.
Main Results:
- No statistically significant differences were observed in controller medication use, systemic corticosteroid prescriptions, or FEV1/FVC% between weight groups.
- A statistically significant difference was found in FEV1% predicted (p = .004).
- Overweight children exhibited the highest mean FEV1% (92.47 ± 16.74%), with significant differences noted between normal weight and overweight, and overweight and obese groups.
Conclusions:
- Objective asthma control, as measured by lung function and medication burden, did not show a statistically significant decline in overweight or obese pediatric asthma patients compared to normal weight peers.
- Despite subjective reports of increased symptoms in obese children, objective data in this study did not support a link to poorer asthma control.
- Further research may be warranted to explore the discrepancy between subjective symptom reporting and objective lung function measures in pediatric asthma and obesity.
Purpose:
To explore if being overweight or obese influenced asthma control in pediatric patients ages 7-18 years with persistent asthma seen in an asthma specialty office.
Data Sources:
A retrospective chart analysis of children with an asthma diagnosis seen within an asthma specialty practice from December 1, 2009 to May 31, 2010 was utilized. Normal weight, overweight, and obese children were compared. The following four variables were examined: the number of controller asthma medications prescribed; the number of systemic corticosteroids prescribed in 1 year for asthma exacerbations; FEV1 % of predicted; and FEV1 /FVC% of predicted.
Conclusions:
No statistically significant difference was found between the three weight groups for the number of controller medications prescribed, number of systemic corticosteroids in 1 year, or FEV1 /FVC. A statistically significant difference was found for FEV1 %, F (2,430) = 5.51, p = .004. Overweight children had the highest mean FEV1 %, 92.47 ± 16.74%. A statistically significant difference was found between the normal weight and overweight groups, p = .0104 and the overweight and obese groups, p = .0233.
Implications For Practice:
In clinical practice, obese children often report more asthma symptoms. This inquiry did not show an objective decline in asthma control associated with overweight or obesity.
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Asthma-III: Symptoms and Complications
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