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Updated: May 6, 2026

Imaging the Root Hair Morphology of Arabidopsis Seedlings in a Two-layer Microfluidic Platform

Imaging the Root Hair Morphology of Arabidopsis Seedlings in a Two-layer Microfluidic Platform

Published on: August 15, 2017

A new approach to root formation.

Mehdi Vatanpour¹, Mina Zarei, Maryam Javidi

¹Department of Endodontics, Dental School, Islamic Azad University , Tehran, Iran.

Iranian Endodontic Journal

|October 31, 2013

Summary

Promoting Hertwig

Area of Science:

Endodontics
Regenerative dentistry

Background:

Treatment of open apex teeth with necrotic pulp presents a significant clinical challenge in endodontics.
Root formation in immature teeth with open apices is often incomplete, complicating standard endodontic procedures.

Purpose of the Study:

To investigate the potential for root formation in open apex teeth with necrotic pulp.
To explore the role of Hertwig's epithelial root sheath remnants and epithelial rests of Malassez in root development.

Main Methods:

Review of endodontic treatment principles for immature teeth.
Discussion of the biological mechanisms involving epithelial remnants in root development.
Emphasis on the importance of thorough root canal irrigation.

Keywords:

Hertwig’s root sheath IGFs Tooth root formation

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Related Experiment Videos

Last Updated: May 6, 2026

Imaging the Root Hair Morphology of Arabidopsis Seedlings in a Two-layer Microfluidic Platform

Imaging the Root Hair Morphology of Arabidopsis Seedlings in a Two-layer Microfluidic Platform

Published on: August 15, 2017

A Simple Protocol for Mapping the Plant Root System Architecture Traits

A Simple Protocol for Mapping the Plant Root System Architecture Traits

Published on: February 10, 2023

Biomimetic Replication of Root Surface Microstructure using Alteration of Soft Lithography

Biomimetic Replication of Root Surface Microstructure using Alteration of Soft Lithography

Published on: August 5, 2020

Main Results:

The presence and promotion of Hertwig's epithelial root sheath remnants appear crucial for root formation.
Epithelial rests of Malassez may also contribute to the regenerative process.
Effective root canal irrigation is a key factor in facilitating these regenerative events.

Conclusions:

Root formation in open apex teeth with necrotic pulp is achievable.
Stimulating Hertwig's epithelial root sheath remnants and epithelial rests of Malassez, coupled with meticulous irrigation, can promote root development.