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Updated: May 6, 2026

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
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Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach

Published on: June 10, 2021

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Modular access to N-substituted cis-3,5-diaminopiperidines

Aurélie Blond1, Paul Dockerty, Raquel Álvarez

  • 1Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques, Faculté des Sciences Fondamentales et Biomédicales, UMR8601, CNRS-Paris Descartes University , 45 rue des Saints Pères, 75006 Paris, France.

The Journal of Organic Chemistry
|November 1, 2013
PubMed
Summary

Researchers developed a new synthetic route to create N-substituted cis-3,5-diaminopiperidines. This method offers a simple and versatile way to access diverse, RNA-friendly molecular fragments.

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