Related Experiment Video
Updated: May 6, 2026

Isolation of Leukocytes from Human Breast Milk for Use in an Antibody-dependent Cellular Phagocytosis Assay of HIV Targets
Published on: September 6, 2019
Motor development of infants exposed to maternal human immunodeficiency virus (HIV) but not infected
Dafne Herrero, Paulo Rogério Gallo, Mahmi Fujimori
1Departamento de Saúde Materno-Infantil da Faculdade de saúde, Pública da Universidade de São Paulo, São Paulo, Brasil. luiz.abreu@fmabc.br.
Background:
To assess the motor development of infants exposed to maternal human immunodeficiency virus (HIV).
Methods:
Thirty infants were assessed in the period from November 2009 to March 2010 at the AIDS Reference and Training Centre, in São Paulo, Brazil. The assessment instrument used in the research was the Alberta Infant Motor Scale (AIMS). All 30 infants used the antiretroviral drug properly for 42 consecutive days, in accordance with the protocol of the World Health Organization.
Results:
Out of the total number of infants, 27 (90%) had proper motor performance and 3 (10%) presented motor delay, according to the AIMS.
Discussion:
This study demonstrated that only 10% of the assessed group had developmental delay and no relation with environmental variables was detected, such as maternal level of education, social and economic issues, maternal practices, attendance at the day care center, and drug use during pregnancy. It is important to emphasize the necessity of studies with a larger number of participants.
Related Concept Videos
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Development of Human Microbiota
Immunodeficiency Diseases
There are three main causes of immunodeficiency...
Cytomegalovirus Disease
Sexually Transmitted Infections

