Related Experiment Video
Updated: May 6, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Management of subclavian artery in-stent restenosis
Anil Verma1, John P Reilly, Christopher J White
1Department of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinic Foundation, New Orleans, LA, USA.
Insights
Subclavian artery stenosis can cause serious health issues. Balloon angioplasty alone may be a viable treatment for subclavian in-stent restenosis when results are excellent, offering an alternative to repeat stenting.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Endovascular Interventions
Background:
- Subclavian and brachiocephalic artery stenosis can lead to ischemia in the upper extremities, brain, and heart.
- Endovascular revascularization, particularly stenting, is the primary treatment for subclavian artery stenosis.
- In-stent restenosis is a known complication, treatable with angioplasty or repeat stenting.
Observation:
- This case report details the management of subclavian in-stent restenosis.
- The treatment involved percutaneous transluminal angioplasty using only balloon angioplasty.
- Excellent angiographic results were achieved with this approach.
Findings:
- Balloon angioplasty alone can be an effective treatment for subclavian in-stent restenosis.
- This approach offers a reasonable alternative to primary stenting in select cases.
- Further data is needed to compare primary stenting versus provisional stenting for subclavian in-stent restenosis.
Implications:
- This finding suggests a less invasive treatment option for subclavian in-stent restenosis.
- It may help avoid repeat stenting in patients with favorable angioplasty outcomes.
- This approach could potentially reduce costs and complications associated with stenting.
Abstract:
Stenotic and occlusive diseases of the subclavian and brachiocephalic arteries can cause a significant morbidity as it can lead to symptomatic ischemia affecting the upper extremities, brain and, in some cases, the heart. An endovascular approach with primary stenting or provisional stenting has become the primary modality of revascularization of subclavian artery stenosis. In-stent restenosis can be treated with percutaneous transluminal angioplasty or repeat stenting and although stents offer superior long-term patency over balloon angioplasty alone for de novo lesions, there are no data regarding primary versus provisional stenting in subclavian in-stent restenosis. Here we describe a case of subclavian in-stent restenosis treated with just balloon angioplasty and demonstrate that provisional stenting with angioplasty alone when the percutaneous transluminal angioplasty results are excellent is a reasonable alternative to primary stent placement for subclavian in-stent restenosis.
Related Concept Videos
Peripheral Artery Disease III: Interprofessional Care
Coronary Artery Disease V: Interprofessional Care
Angina IV: Management
Acute Coronary Syndrome IV: Interprofessional Care
Atherosclerosis III: Management
Aortic Regurgitation III: Medical Management

