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Recurrent epistaxis in children
1Glasgow Royal Infirmary, Glasgow, UK.
Insights
Recurrent nosebleeds in children are common but often resolve. This review examines treatments like antiseptic cream, petroleum jelly, and silver nitrate cautery for persistent cases.
Area of Science:
- Pediatric Otolaryngology
- Evidence-Based Medicine
Background:
- Recurrent idiopathic epistaxis affects up to 9% of children.
- Most cases originate from the anterior nasal septum.
- The majority of children outgrow recurrent nosebleeds.
Purpose of the Study:
- To evaluate the effectiveness and safety of treatments for recurrent idiopathic epistaxis in children.
- To answer the clinical question: What are the effects of treatments for recurrent idiopathic epistaxis in children?
Main Methods:
- Systematic review of medical literature.
- Searched Medline, Embase, The Cochrane Library up to June 2013.
- Included harms alerts from FDA and MHRA.
- GRADE evaluation of evidence quality for interventions.
Main Results:
- Five systematic reviews or randomized controlled trials (RCTs) met inclusion criteria.
- Evidence quality for interventions was assessed using GRADE.
Conclusions:
- Presents information on the effectiveness and safety of antiseptic cream (chlorhexidine hydrochloride, neomycin sulfate, or both), petroleum jelly, and silver nitrate cautery.
- Provides a review of interventions for recurrent idiopathic epistaxis in pediatric populations.
Introduction:
Up to 9% of children may have recurrent nosebleeds, usually originating from the anterior septum, but the majority grow out of the problem.
Methods And Outcomes:
We conducted a systematic review and aimed to answer the following clinical question: What are the effects of treatments for recurrent idiopathic epistaxis in children? We searched: Medline, Embase, The Cochrane Library, and other important databases up to June 2013 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
Results:
We found 5 systematic reviews or RCTs that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
Conclusions:
In this systematic review we present information relating to the effectiveness and safety of the following interventions: antiseptic cream (containing chlorhexidine hydrochloride, neomycin sulfate, or both), petroleum jelly, and silver nitrate cautery.
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