Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Availability Heuristic01:08

The Availability Heuristic

6.1K
A heuristic is a general problem-solving framework (Tversky & Kahneman, 1974). You can think of these as mental shortcuts that are used to solve problems. Different types of heuristics are used in different types of situations, and the impulse to use a heuristic occurs when one of five conditions is met (Pratkanis, 1989):
6.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fragmentation of Single-Particle Strength around the Doubly Magic Nucleus  ^{132}Sn and the Position of the 0f_{5/2} Proton-Hole State in ^{131}In.

Physical review letters·2020
Same author

Role of the Δ Resonance in the Population of a Four-Nucleon State in the ^{56}Fe→^{54}Fe Reaction at Relativistic Energies.

Physical review letters·2016
Same author

Isospin Mixing in ^{80}Zr: From Finite to Zero Temperature.

Physical review letters·2015
Same author

Hindered Gamow-Teller decay to the odd-odd N=Z (62)Ga: absence of proton-neutron T=0 condensate in A=62.

Physical review letters·2014
Same author

Isospin character of low-lying pygmy dipole states in 208Pb via inelastic scattering of 17O ions.

Physical review letters·2014
Same author

Coulomb excitation of 104Sn and the strength of the 100Sn shell closure.

Physical review letters·2013
Same journal

Unhealthy fat distribution as a sex-specific predictor of declining hippocampus insulin sensitivity.

Diabetologia·2026
Same journal

Baseline and longitudinal joint associations of alcohol consumption and obesity with diabetes risk: evaluating multiplicative and additive interactions.

Diabetologia·2026
Same journal

GIP contributes to postprandial regulation of splanchnic blood supply in humans with type 2 diabetes: a randomised, single-blinded, placebo-controlled, crossover study.

Diabetologia·2026
Same journal

Correction: Analysis of glycaemic control with a connected smart pen cap in adults with type 1 diabetes: a randomised, open-label, parallel-group trial.

Diabetologia·2026
Same journal

History of infertility, risk of type 2 diabetes and HbA<sub>1c</sub> levels in the Nurses' Health Study II.

Diabetologia·2026
Same journal

Delayed maturation of the milk microbiome in women with type 1 diabetes.

Diabetologia·2026
See all related articles

Related Experiment Video

Updated: May 6, 2026

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities
12:33

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

Published on: November 15, 2013

50.6K

[Not Available].

E Siess1, A Teinzer, O Wieland

  • 1Laboratorium für Klinische Chemie und Biochemie der II. Medizinischen Universitätsklinik, München.

Diabetologia
|November 1, 2013
PubMed
Summary
This summary is machine-generated.

This study introduces a streamlined assay for measuring insulin-like activity using adipose tissue glucose oxidation. The method is efficient, requiring minimal resources, and accurately quantifies insulin-like activity in human serum.

More Related Videos

Ex Vivo Assessment of Contractility, Fatigability and Alternans in Isolated Skeletal Muscles
14:02

Ex Vivo Assessment of Contractility, Fatigability and Alternans in Isolated Skeletal Muscles

Published on: November 1, 2012

24.1K
A Submerged Filter Paper Sandwich for Long-term Ex Ovo Time-lapse Imaging of Early Chick Embryos
07:29

A Submerged Filter Paper Sandwich for Long-term Ex Ovo Time-lapse Imaging of Early Chick Embryos

Published on: December 28, 2016

24.4K

Related Experiment Videos

Last Updated: May 6, 2026

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities
12:33

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

Published on: November 15, 2013

50.6K
Ex Vivo Assessment of Contractility, Fatigability and Alternans in Isolated Skeletal Muscles
14:02

Ex Vivo Assessment of Contractility, Fatigability and Alternans in Isolated Skeletal Muscles

Published on: November 1, 2012

24.1K
A Submerged Filter Paper Sandwich for Long-term Ex Ovo Time-lapse Imaging of Early Chick Embryos
07:29

A Submerged Filter Paper Sandwich for Long-term Ex Ovo Time-lapse Imaging of Early Chick Embryos

Published on: December 28, 2016

24.4K

Area of Science:

  • Biochemistry
  • Endocrinology
  • Metabolic Research

Context:

  • Insulin-like activity measurement is crucial for understanding metabolic regulation and diagnosing endocrine disorders.
  • Existing methods can be resource-intensive and time-consuming.
  • Adipose tissue plays a key role in glucose metabolism and insulin action.

Purpose:

  • To develop and validate a simplified, efficient method for quantifying insulin-like activity.
  • To assess the reliability and precision of the new assay.
  • To investigate the behavior of insulin-like activity in human serum using this method.

Summary:

  • A novel assay measures insulin-like activity by quantifying the stimulation of glucose-1-(14)C oxidation in adipose tissue.
  • The method allows for 40 determinations per day with high precision (index ~0.13) using only two rats.
  • Applied to dialyzed human serum, it revealed a wide range of insulin-like activity (78-1020 μU/ml), with ~40% suppressible by insulin antibodies.
  • Dilution studies highlighted potential artifacts when using standard curves in buffer versus serum.

Impact:

  • Provides a more accessible and efficient tool for researchers and clinicians studying insulin action and metabolic diseases.
  • Offers insights into the complexities of insulin-like activity measurement in biological samples.
  • Contributes to a better understanding of insulin's role in glucose homeostasis and potential therapeutic targets.