Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

The Availability Heuristic

The Availability Heuristic

A heuristic is a general problem-solving framework (Tversky & Kahneman, 1974). You can think of these as mental shortcuts that are used to solve problems. Different types of heuristics are used in different types of situations, and the impulse to use a heuristic occurs when one of five conditions is met (Pratkanis, 1989):

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[Proceedings: Pericarditis uremica, management of tamponated effusions using a percutaneously inserted indwelling pericardial catheter].

Helvetica medica acta·1974

Same author

[Uremic pericarditis: treatment of cardiac tamponade with a percutaneously inserted pericardial indwelling catheter].

Schweizerische medizinische Wochenschrift·1973

Same author

[Renovascular hypertension and neurofibromatosis].

Schweizerische medizinische Wochenschrift·1973

Same author

[Course and conservative therapy in chronic inflammatory kidney diseases].

Zeitschrift fur Krankenpflege. Revue suisse des infirmieres·1973

Same author

[Intensive care of patients with heart surgery].

Therapeutische Umschau. Revue therapeutique·1970

Same author

[Unusual course of a pheochromocytoma].

Praxis·1969

Search research articles

Related Experiment Video

Updated: May 6, 2026

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

Published on: November 15, 2013

[Not Available].

¹Pathologischen Institut des Kantonsspitals Winterthur, Deutschland.

|November 1, 2013

Summary

This summary is machine-generated.

Homogeneous capillary lesions were found in diabetic patients with and without Kimmelstiel-Wilson glomerulosclerosis, but not in controls. These pancreatic capillary changes may indicate diabetic microvascular complications.

More Related Videos

Ex Vivo Assessment of Contractility, Fatigability and Alternans in Isolated Skeletal Muscles

Ex Vivo Assessment of Contractility, Fatigability and Alternans in Isolated Skeletal Muscles

Published on: November 1, 2012

A Submerged Filter Paper Sandwich for Long-term Ex Ovo Time-lapse Imaging of Early Chick Embryos

A Submerged Filter Paper Sandwich for Long-term Ex Ovo Time-lapse Imaging of Early Chick Embryos

Published on: December 28, 2016

Related Experiment Videos

Last Updated: May 6, 2026

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

Published on: November 15, 2013

Ex Vivo Assessment of Contractility, Fatigability and Alternans in Isolated Skeletal Muscles

Ex Vivo Assessment of Contractility, Fatigability and Alternans in Isolated Skeletal Muscles

Published on: November 1, 2012

A Submerged Filter Paper Sandwich for Long-term Ex Ovo Time-lapse Imaging of Early Chick Embryos

A Submerged Filter Paper Sandwich for Long-term Ex Ovo Time-lapse Imaging of Early Chick Embryos

Published on: December 28, 2016

Area of Science:

Pathology
Diabetology
Nephrology

Context:

Diabetic nephropathy is a significant complication of diabetes mellitus.
Kimmelstiel-Wilson glomerulosclerosis is a characteristic lesion of diabetic nephropathy.
Pancreatic microvasculature changes in diabetes are not well understood.

Purpose:

To investigate the presence and characteristics of homogeneous capillary lesions in the pancreas of diabetic patients.
To compare the occurrence of these lesions in patients with and without Kimmelstiel-Wilson glomerulosclerosis.
To differentiate these homogeneous lesions from other pancreatic microvascular changes.

Summary:

Homogeneous, PAS-positive capillary wall thickening was examined in pancreatic samples from 25 diabetics with Kimmelstiel-Wilson glomerulosclerosis, 54 diabetics without, and 70 non-diabetic controls.
These lesions were observed in approximately one-third of cases with glomerulosclerosis, one-seventh of cases without, and none of the controls, primarily in extrainsular capillaries.
Histochemical analysis distinguished these homogeneous lesions from nodular Kimmelstiel-Wilson lesions and islet hyalinosis, with their pathogenesis remaining unclear.

Impact:

Identifies a distinct microvascular lesion in the pancreas associated with diabetes.
Suggests potential markers for diabetic microvascular disease beyond the kidney.
Highlights the need for further research into the pathogenesis and clinical significance of pancreatic capillary lesions in diabetes.