Related Experiment Video
Updated: May 6, 2026

Determination of the Mating Efficiency of Haploids in Saccharomyces cerevisiae
Published on: December 2, 2022
An α-mating-type-specific mutation causing specific defect in sexual agglutinability in the yeast Saccharomyces
1Biological Institute, Faculty of Science, Nagoya University, 464, Chikusa-ku, Nagoya, Japan.
Abstract:
We have identified a recessive α-mating-type-specific gene agαl causing agglutinability defect without significant effects on other sexual activities. a cells carrying agαl showed sexual agglutination with α cells but α cells carrying agαl showed sexual agglutination with neither α cells nor a cells. α cells carrying agαl produced α pheromone and responded to a pheromone just like wild α cells. α cells carrying agαl showed a little decreased but significant mating ability when tested on solid media or membrane filter. The agαl mutant is different from any α-specific ste mutants found so far in many sexual activities. The agαl gene is recessive, and unlinked to the mating type locus. Biological significance of the α mating type agglutinability is discussed based on the results obtained with the mutant.
More Related Videos
11:57Saccharomyces cerevisiae Models of Alzheimer's Disease to Screen Genes, Mutations, and Chemicals Affecting Amyloid Beta Production by γ-Secretase
Published on: June 24, 2025
08:24A Method to Study α-Synuclein Toxicity and Aggregation Using a Humanized Yeast Model
Published on: November 25, 2022
Related Concept Videos
Yeast Signaling
Lethal Alleles
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...
Mismatch Repair
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
Sex-linked Disorders
Mutations
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...