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Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Alzheimer Disease l: Introduction01:29

Alzheimer Disease l: Introduction

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Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
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Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

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In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

868
As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
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Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

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The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
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Related Experiment Video

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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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Chronic daily headache in the elderly.

Aynur Özge1

  • 1Mersin University School of Medicine, Eğriçam mah. GMK Bulvarı Kasım Ekenler Sitesi C Bl, D:2, 33160, Yenişehir, Mersin, Turkey, aynurozge@gmail.com.

Current Pain and Headache Reports
|November 1, 2013
PubMed
Summary

Headache disorders in the elderly are common but often missed. Accurate diagnosis and management are crucial for improving quality of life in this growing population.

Area of Science:

  • Neurology
  • Geriatrics

Background:

  • Headache disorders are prevalent across all age groups, including the elderly.
  • Elderly populations are under-represented in headache research, leading to under-recognition and undertreatment.
  • Chronic daily headache (CDH) is a significant subtype impacting quality of life.

Purpose of the Study:

  • To highlight the challenges in diagnosing and managing headache disorders in the elderly.
  • To emphasize the need for accurate diagnosis and differentiation from secondary causes in older adults.

Main Methods:

  • Review of existing literature on headache disorders in the elderly.
  • Classification of chronic daily headache based on duration (long >4 hours, short <4 hours).
  • Consideration of diagnostic challenges unique to the aging population.

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Main Results:

  • Limited data exists on headache disorders specifically in elderly populations.
  • Common long-duration CDH include chronic migraine and chronic tension-type headache.
  • Rarer short-duration CDH include chronic cluster headache and hypnic headache.

Conclusions:

  • Diagnosing and managing CDH in the elderly presents unique challenges.
  • Differentiating primary headaches from secondary causes is critical in older adults.
  • Tailored coping strategies are essential for the aging population with headache disorders.