Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

6.2K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
6.2K
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

863
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
863
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

7.6K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
7.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

PET Imaging Characterization of Sphingosine-1-Phosphate Receptor 2 in a Mouse Model of Esophageal Adenocarcinoma and Metastatic Lymph Node.

Molecular pharmaceutics·2026
Same author

Oral [<sup>18</sup>F]-Fluoro-Thia-Heptadecanoic Acid Positron Emission Tomography Reveals Mesenteric-to-Central Lymphatic Flow.

Gastro hep advances·2026
Same author

<i>Circulation: Cardiovascular Imaging's</i> Top 10 Reviewers of 2025 to 2026.

Circulation. Cardiovascular imaging·2025
Same author

Discovery and in vivo evaluation of a fluorine-18 pro-drug tracer for imaging sphingosine-1-phosphate receptor 2 in the brain.

Bioorganic & medicinal chemistry·2025
Same author

Preclinical Evaluation of <sup>64</sup>Cu-LNTH-1363S to Detect Cardiac FAP-Positive Fibroblasts Using PET Imaging.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2025
Same author

Automated production of radiotracer [<sup>18</sup>F]FZTA for imaging sphingosine-1-phosphate receptor 1 (S1PR1) in human.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2025

Related Experiment Video

Updated: May 6, 2026

Autofluorescence Imaging to Evaluate Cellular Metabolism
07:36

Autofluorescence Imaging to Evaluate Cellular Metabolism

Published on: November 15, 2021

4.9K

Recent advances in metabolic imaging.

Robert J Gropler1

  • 1Division of Radiological Sciences, Cardiovascular Imaging Laboratory, Edward Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S. Kingshighway, St. Louis, MO, 63110, USA, Groplerr@mir.wustl.edu.

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
|November 1, 2013
PubMed
Summary

Abnormalities in myocardial substrate metabolism are central to cardiac diseases. Advances in metabolic imaging offer new insights and potential clinical applications for cardiovascular research.

More Related Videos

Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging
11:43

Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging

Published on: December 30, 2016

10.1K
Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer
06:51

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

Published on: July 21, 2018

19.0K

Related Experiment Videos

Last Updated: May 6, 2026

Autofluorescence Imaging to Evaluate Cellular Metabolism
07:36

Autofluorescence Imaging to Evaluate Cellular Metabolism

Published on: November 15, 2021

4.9K
Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging
11:43

Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging

Published on: December 30, 2016

10.1K
Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer
06:51

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

Published on: July 21, 2018

19.0K

Area of Science:

  • Cardiovascular Research
  • Metabolic Imaging
  • Molecular Biology

Background:

  • Myocardial substrate metabolism abnormalities are key in cardiac diseases like heart failure and diabetes.
  • Numerous imaging tools and drug discovery efforts target these metabolic changes.
  • Recent insights reveal metabolism's broad impact on cardiac function, gene expression, and viability.

Purpose of the Study:

  • To review key advances in cardiac metabolic imaging since 2005.
  • To highlight the contribution of metabolic imaging to cardiovascular research.
  • To propose potential new clinical applications for metabolic imaging.

Main Methods:

  • Review of recent literature on myocardial metabolism and cardiac disease.
  • Description of advancements in instrumentation and radiopharmaceutical design for metabolic imaging.
  • Integration of molecular biology techniques and genetic models to understand metabolic perturbations.

Main Results:

  • Significant progress in understanding how metabolic perturbations contribute to various cardiac conditions.
  • Development of advanced small animal imaging techniques.
  • Near completion of the translational pathway from in-vitro measurements to human applications.

Conclusions:

  • Metabolic imaging has significantly advanced cardiovascular research.
  • New insights into cardiac metabolism offer potential for novel diagnostic and therapeutic strategies.
  • Further development and application of metabolic imaging hold promise for clinical translation.