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The nose is composed of an observable exterior segment (external nose) and an internal segment within the skull known as the nasal cavity (internal nose). The external nose, visible on the face, consists of a framework of bone and hyaline cartilage enveloped in skin and muscle and lined with a mucous membrane. This structure is supported by the frontal bone, nasal bones, and maxillary bone and is supplemented by a cartilaginous framework comprising the septal nasal cartilage, lateral nasal...
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Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...
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In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...
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Quantification of Orofacial Phenotypes in Xenopus
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Leporine (cleft lip) nose.

J L Frontera Vaca1, A J Pardina

  • 1, 856 Obispo Trejo, 5000, Córdoba, Argentina.

Aesthetic Plastic Surgery
|November 1, 2013
PubMed
Summary

This study details surgical techniques for correcting the leporine nose in unilateral cleft lip cases. It explores how variations in columella length influence surgical outcomes.

Area of Science:

  • Plastic Surgery
  • Craniofacial Surgery
  • Pediatric Surgery

Background:

  • Unilateral cleft lip often presents with a leporine nose deformity.
  • Accurate surgical correction is crucial for aesthetic and functional outcomes.

Purpose of the Study:

  • To describe the surgical technique for leporine nose correction in unilateral cleft lip.
  • To analyze variations in technique based on columella length.

Main Methods:

  • Review of surgical procedures for leporine nose correction.
  • Analysis of technique modifications related to columella length.

Main Results:

  • Specific surgical steps are outlined for effective leporine nose correction.
  • Columella length is a key factor determining surgical approach variations.

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Conclusions:

  • The described surgical technique provides a framework for leporine nose correction.
  • Tailoring the technique to columella length optimizes results in unilateral cleft lip repair.