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Updated: May 6, 2026
Mitochondrial Isolation from Skeletal Muscle
Published on: March 30, 2011
An ultrastructural study of isolated rat skeletal muscle mitochondria in various metabolic states
1Laboratory of Chemical Biology and Department of Zoology, University of Michigan, 48104, Ann Arbor, Michigan.
Abstract:
An electron microscopic examination was made of isolated rat skeletal muscle mitochondria in various functional states. Shifts in the inner membrane ultrastructure of populations of mitochondria were observed under certain conditions. However, ultrastructural transformations reported by others during rapid changes in biochemical states were not observed in skeletal muscle mitochondria. There does not appear to be a strict correlation between metabolic states and ultrastructural states in isolated rat skeletal muscle mitochondria as has been observed in isolated mitochondria from several other tissue types.
