Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genomics02:02

Genomics

35.6K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
35.6K
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

5.9K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.9K
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

12.9K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
12.9K
Animal Mitochondrial Genetics02:59

Animal Mitochondrial Genetics

7.8K
Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
7.8K
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

2.5K
2.5K
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

7.6K
While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
7.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Census and genetic analysis of the United States marmoset population.

bioRxiv : the preprint server for biology·2026
Same author

Long-read structural variant discovery and targeted short read genotyping enables population scale characterization of structural variation in rhesus macaques.

Genome biology·2025
Same author

Inbreeding and deleterious variation in South Asian populations.

Scientific reports·2025
Same author

Analysis of whole-exome data of nonobese NAFLD patients from India reveals association with new markers on functionally relevant genes and pathways.

Journal of genetics·2025
Same author

Polygenic risk score portability for common diseases across genetically diverse populations.

Human genomics·2024
Same author

Genetic regulatory effects in response to a high-cholesterol, high-fat diet in baboons.

Cell genomics·2024
Same journal

Laboratory Codes in Nomenclature and Scientific Communication (Advancing Organism Nomenclature in Scientific Communication to Improve Research Reporting and Reproducibility).

ILAR journal·2022
Same journal

History of the National Academies of Sciences, Engineering, and Medicine's Institute for Laboratory Animal Research.

ILAR journal·2022
Same journal

History of the International Council for Laboratory Animal Science.

ILAR journal·2022
Same journal

International Standardized Nomenclature for Outbred Stocks of Laboratory Animals.

ILAR journal·2022
Same journal

Rapid Response by Laboratory Animal Research Institutions During the COVID-19 Pandemic: Key Lessons Learned From a 2021 National Academies of Sciences, Engineering, and Medicine Workshop.

ILAR journal·2022
Same journal

Beyond the Laboratory: Emerging Landscape of Animal Studies - the Influence of National Academies of Sciences Activities and Publications.

ILAR journal·2022
See all related articles

Related Experiment Video

Updated: May 6, 2026

A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes
09:10

A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes

Published on: May 22, 2018

10.6K

Great ape genomics.

Jeffrey D Wall

    ILAR Journal
    |November 1, 2013
    PubMed
    Summary
    This summary is machine-generated.

    Great apes, our closest relatives, offer insights into human biology and history. Genome-wide data reveals evolutionary genetics, deepening our understanding of both humans and these fascinating species.

    Keywords:
    conservation geneticsdemographyevolutiongreat apesnatural selectionpopulation size

    More Related Videos

    Tissue Collection of Bats for -Omics Analyses and Primary Cell Culture
    15:31

    Tissue Collection of Bats for -Omics Analyses and Primary Cell Culture

    Published on: October 23, 2019

    12.0K
    Author Spotlight: Investigating the Role of Repetitive DNA Misregulation in Cancer Initiation and Immunotherapy Resistance
    04:58

    Author Spotlight: Investigating the Role of Repetitive DNA Misregulation in Cancer Initiation and Immunotherapy Resistance

    Published on: December 13, 2024

    3.8K

    Related Experiment Videos

    Last Updated: May 6, 2026

    A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes
    09:10

    A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes

    Published on: May 22, 2018

    10.6K
    Tissue Collection of Bats for -Omics Analyses and Primary Cell Culture
    15:31

    Tissue Collection of Bats for -Omics Analyses and Primary Cell Culture

    Published on: October 23, 2019

    12.0K
    Author Spotlight: Investigating the Role of Repetitive DNA Misregulation in Cancer Initiation and Immunotherapy Resistance
    04:58

    Author Spotlight: Investigating the Role of Repetitive DNA Misregulation in Cancer Initiation and Immunotherapy Resistance

    Published on: December 13, 2024

    3.8K

    Area of Science:

    • Primatology
    • Evolutionary Genetics
    • Genomics

    Background:

    • Great apes (chimpanzees, bonobos, gorillas, orangutans) are humans' closest living relatives.
    • They inhabit Central African and Southeast Asian tropical rainforests.
    • Shared cognitive, physiological, and morphological traits highlight their evolutionary connection to humans.

    Purpose of the Study:

    • To review how genome-wide data from great apes enhances understanding of these species.
    • To explore the implications of great ape genomics for human evolutionary genetics.
    • To elucidate human biology and history through the study of great apes.

    Main Methods:

    • Review of recent scientific literature.
    • Analysis of genome-wide data from great ape populations.
    • Comparative genomics studies.

    Main Results:

    • Genome-wide data provides unprecedented insights into great ape evolutionary history.
    • Comparative genomic analyses reveal genetic underpinnings of human-specific traits.
    • Understanding great ape genetics illuminates human origins and evolutionary pathways.

    Conclusions:

    • Great apes are invaluable models for understanding human evolution.
    • Genomic data is revolutionizing the study of primate evolution and human origins.
    • Continued research on great ape genomes is crucial for advancing evolutionary genetics.