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Updated: May 6, 2026
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Published on: January 6, 2011
Pallidotomy after chronic deep brain stimulation
Kristian J Bulluss1, Erlick A Pereira, Carole Joint
1Oxford Functional Neurosurgery and Experimental Neurology Group, Nuffield Department of Surgery, University of Oxford, and Department of Neurological Surgery, John Radcliffe Hospital, Oxford, United Kingdom.
Abstract:
Recent publications have demonstrated that deep brain stimulation for Parkinson's disease still exerts beneficial effects on tremor, rigidity, and bradykinesia for up to 10 years after implantation of the stimulator. However with the progression of Parkinson's disease, features such as cognitive decline or "freezing" become prominent, and the presence of an implanted and functioning deep brain stimulator can impose a profound burden of care on the clinical team and family. The authors describe their experience in treating 4 patients who underwent removal of the implanted device due to either progressive dementia requiring full-time nursing or due to infection, and who subsequently underwent a unilateral pallidotomy.
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