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A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse
Published on: October 24, 2017
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Should a first trimester dating scan be routine for all pregnancies?
1Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St., OBC-3-010, Boston, MA 02115.
Seminars in Perinatology
|November 2, 2013
Summary
Accurate pregnancy dating is crucial for prenatal care. While first-trimester ultrasound crown-rump length is slightly more accurate than second-trimester ultrasound, the difference may not justify routine first-trimester scans for dating purposes.
Area of Science:
- Obstetrics and Gynecology
- Prenatal Diagnostics
Background:
- Accurate pregnancy dating is essential for clinical decisions and management.
- Last menstrual period (LMP) dating is prone to inaccuracies.
- Ultrasound dating offers improved reliability over LMP estimation.
Purpose of the Study:
- To compare the accuracy of first-trimester ultrasound crown-rump length (CRL) dating with second-trimester ultrasound dating.
- To evaluate if the accuracy difference justifies routine first-trimester dating scans.
Main Methods:
- Comparison of confidence intervals for pregnancy dating using first-trimester ultrasound (CRL).
- Comparison of confidence intervals for pregnancy dating using second-trimester ultrasound (14-20 weeks).
Main Results:
- First-trimester ultrasound CRL dating provides a 95% confidence range of ±5 days.
- Second-trimester ultrasound dating (14-20 weeks) has a 95% confidence range of ±8 days.
- The difference in accuracy is approximately 3 days.
Conclusions:
- First-trimester ultrasound CRL dating is marginally more accurate than second-trimester ultrasound dating.
- The small accuracy improvement does not appear to warrant routine first-trimester scans solely for pregnancy dating.
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