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Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
[Mineral and bone disorders in renal transplantation]
Justine Bacchetta1, Marie-Hélène Lafage-Proust, Roland Chapurlat
1Centre de référence des maladies rénales rares, service de néphrologie et rhumatologie pédiatriques, hôpital Femme-Mère-Enfant, boulevard Pinel, 69677 Bron cedex, France; Institut de génomique fonctionnelle de Lyon (IGFL), École normale supérieure, 69007 Lyon, France; Université de Lyon, 69008 Lyon, France.
Abstract:
The deregulation of bone and mineral metabolism during chronic kidney disease (CKD) is a daily challenge for physicians, its management aiming at decreasing the risk of both fractures and vascular calcifications. Renal transplantation in the context of CKD, with pre-existing renal osteodystrophy as well as nutritional impairment, chronic inflammation, hypogonadism and corticosteroids exposure, represents a major risk factor for bone impairment in the post-transplant period. The aim of this review is therefore to provide an update on the pathophysiology of mineral and bone disorders after renal transplantation.
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