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[Characterization of chromosomal aberrations induced in man by various antimitotic agents]

M F Turchini, A Geneix, B Perissel

Comptes Rendus Des Seances De La Societe De Biologie Et De Ses Filiales

|January 1, 1985

Abstract:

Six antitumoral drugs were tested in human lymphocytes cultures. Our observations pointed out specific abnormalities beside more usual chromosomal aberrations. These lesions are mainly telomeric and chromatidic fusions, chromomerisations and despiralizations. We present an interpretation of these abnormalities.

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