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Long-term outcomes of infants and children undergoing percutaneous endoscopy gastrostomy tube placement

Maireade E McSweeney1, Hongyu Jiang, Amanda J Deutsch

  • 1Department of Medicine, Division of Gastroenterology, Boston Children's Hospital, Harvard Medical School, Boston, MA.

Journal of Pediatric Gastroenterology and Nutrition
|November 2, 2013
PubMed

Insights

Pediatric patients undergoing percutaneous endoscopic gastrostomy (PEG) placement face a high long-term risk of major tube-related complications. These complications can occur many years after the initial PEG procedure.

Area of Science:

  • Pediatric Gastroenterology
  • Medical Device Complications
  • Long-term Patient Outcomes

Background:

  • Percutaneous endoscopic gastrostomy (PEG) is a common procedure for enteral nutrition in children.
  • Long-term outcomes and complication rates following pediatric PEG placement are not well-established.

Purpose of the Study:

  • To investigate the incidence and timing of major tube-related complications in pediatric patients after PEG placement.
  • To assess long-term outcomes, including elective tube removal and mortality, over a 10-year follow-up period.

Main Methods:

  • Retrospective chart review of 138 pediatric patients who underwent PEG placement between April 1999 and December 2000.
  • Kaplan-Meier survival analysis used to evaluate cumulative complication rates and time to complications.
  • Assessment of time to elective tube removal and patient mortality.

Main Results:

  • Median follow-up was 4.98 years. Median time to elective tube removal was 10.2 years.
  • 11% of patients (n=15) experienced at least one major complication.
  • Cumulative incidence of major complications reached 15% by 5.4 years post-placement.

Conclusions:

  • Pediatric patients undergoing PEG placement have a significant long-term risk of morbidity associated with enteral tubes.
  • Major complications can manifest years after the initial PEG procedure, highlighting the need for ongoing monitoring.
  • Further prospective studies are recommended to identify risk factors for PEG-related complications in pediatric populations.
Abstract

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