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Occurrence of Diplococcus pneumoniae in the upper respiratory tract of children
Abstract:
The patterns of colonization of D. pneumoniae were studied over a 46-month period in a group of young children in a day-care center. Forty-four percent of nasal cultures yielded D. pneumoniae. The most frequently isolated serotypes--6, 19, and 23--accounted for 49% of the isolates; the nine most common serotypes included 80% of the isolates. Individual serotypes frequently were carried for several months. Reacquisition of a serotype previously carried occurred frequently. There was limited spread of serotypes among the children despite prolonged contact.
Insights
Streptococcus pneumoniae colonization is common in young children at daycare centers. Serotypes can be carried for months, with frequent reacquisition, but limited spread between children.
Area of Science:
- Pediatric infectious diseases
- Microbiology
- Epidemiology
Background:
- Streptococcus pneumoniae (D. pneumoniae) is a significant cause of childhood illness.
- Understanding colonization patterns is crucial for developing effective prevention strategies.
Purpose of the Study:
- To investigate the colonization patterns of D. pneumoniae in young children attending a daycare center over a 46-month period.
Main Methods:
- Nasal cultures were collected from children over 46 months.
- Isolates were identified, and serotypes were determined.
- Colonization duration and reacquisition were analyzed.
Main Results:
- D. pneumoniae was detected in 44% of nasal cultures.
- Serotypes 6, 19, and 23 were most frequent, comprising 49% of isolates.
- Individual serotypes were carried for extended periods, with frequent reacquisition observed.
- Limited serotype spread occurred among children despite prolonged contact.
Conclusions:
- D. pneumoniae colonization is persistent in young children in daycare settings.
- Serotype dynamics, including prolonged carriage and reacquisition, are complex.
- The limited inter-child spread suggests other factors influence transmission within this environment.