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Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
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It is not uncommon for complete drug pharmacokinetic profiles to remain elusive in pharmacokinetics. This necessitates certain educated assumptions by pharmacokineticists to determine appropriate dosage regimens without comprehensive pharmacokinetic data from animal or human studies. One prevalent assumption is setting the bioavailability factor, denoted as F, to 1 or 100%. This assumption caters to the scenario where a drug doesn't achieve full systemic absorption, resulting in the patient...
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E-PRESCRIBING AND PATIENT SAFETY: RESULTS FROM A MIXED METHOD STUDY.

Kate L Lapane1, Molly E Waring, Catherine Dubé

  • 1Department of Epidemiology and Community Health, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia ; Department of Community Health, Warren Alpert Medical School of Brown University, Providence, Rhode Island.

The American Journal of Pharmacy Benefits
|November 2, 2013
PubMed
Summary

Electronic prescribing (e-prescribing) systems offer benefits like remote medication list access but do not eliminate errors. Clinicians report new types of prescription errors emerge with e-prescribing implementation.

Keywords:
electronic prescribingprimary caretechnology assessment

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Area of Science:

  • Health Informatics
  • Patient Safety
  • Ambulatory Care

Background:

  • Electronic prescribing (e-prescribing) systems are increasingly adopted in ambulatory care settings.
  • Assessing the impact of these systems on patient safety is crucial for optimizing healthcare delivery.

Purpose of the Study:

  • To explore ambulatory care clinicians' perspectives on how e-prescribing systems influence patient safety outcomes.
  • To understand the perceived benefits and drawbacks of e-prescribing technology in clinical practice.

Main Methods:

  • A mixed-method study involving surveys and focus groups with clinicians and staff across 64 practices in six U.S. states.
  • Utilized both web-based and paper surveys to gather a comprehensive range of clinician opinions.

Main Results:

  • Clinicians highly value features such as integrated medication lists from other providers and remote patient medication access.
  • However, providers believe e-prescribing transforms rather than eliminates medication errors, introducing new issues like incorrect dosing, wrong drug selection, and duplicate prescriptions.

Conclusions:

  • The integration of e-prescribing technology necessitates careful consideration of clinician experiences to achieve intended patient safety improvements.
  • Realizing the full potential of e-prescribing for patient safety requires addressing the practical challenges and new error types identified by frontline providers.