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Related Experiment Video

Updated: May 6, 2026

Aseptic Laboratory Techniques: Volume Transfers with Serological Pipettes and Micropipettors

Aseptic Laboratory Techniques: Volume Transfers with Serological Pipettes and Micropipettors

Published on: May 31, 2012

Automatic reservoir for serial pipetting.

G W Moskowitz¹, L M Levy

¹Div. of Nuclear Medicine, Long Island Jewish-Hillside Medical Ctr., New Hyde Park, NY 11040, USA.

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine

|November 5, 2013

Summary

This summary is machine-generated.

A new automatic reservoir for serial pipetting reduces reagent costs and solution loss in radioimmunoassay (RIA) procedures. This cost-effective device maintains assay precision and accuracy, proving valuable for low-volume assays.

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Area of Science:

Biochemistry
Laboratory Automation
Analytical Chemistry

Background:

Radioimmunoassay (RIA) procedures often require precise reagent handling.
Minimizing reagent waste is crucial, especially with expensive antibody reagents.
Automated systems can enhance efficiency and reproducibility in laboratory assays.

Purpose of the Study:

To develop and evaluate an automatic reservoir for serial pipetting in RIA.
To assess the impact of the device on reagent consumption, cost, and assay performance.
To determine the utility of the reservoir in conjunction with automatic pipetting stations.

Main Methods:

Construction of a novel automatic reservoir for serial pipetting.
Integration of the reservoir with an automatic pipetting station for RIA.
Evaluation of priming volume, solution loss, and overall cost.
Assessment of assay precision and accuracy compared to standard methods.

Main Results:

The automatic reservoir demonstrated negligible priming volume and minimal solution loss.
Overall costs were lowered, particularly for expensive antibody reagents.
The device did not adversely affect the precision or accuracy of radioimmunoassay determinations.
Significant economies were achieved, especially in low-volume assay applications.

Conclusions:

The developed automatic reservoir is a valuable tool for serial pipetting in RIA.
It offers significant cost savings by reducing reagent waste.
The device maintains the integrity of assay precision and accuracy.
It is particularly beneficial for optimizing low-volume radioimmunoassays.