Long-term outcomes of moderately preterm, late preterm, and early term infants

Betty Vohr1

  • 1Department of Pediatrics, Women & Infants Hospital, 101 Dudley Street, Providence, RI 02905, USA.

Clinics in Perinatology
|November 5, 2013
PubMed

Insights

Moderate preterm (MPT) and late preterm (LPT) infants face higher risks for developmental and behavioral issues. Each week of reduced gestational age below 39 weeks correlates with increased adverse outcomes.

Area of Science:

  • Neonatal Medicine
  • Developmental Pediatrics
  • Public Health

Background:

  • Moderate preterm (MPT) infants (32-33 weeks) and late preterm (LPT) infants (34-36 weeks) constitute over 80% of US premature births.
  • Emerging evidence indicates elevated risks for MPT and LPT infants regarding neurologic impairments, developmental delays, and behavioral problems.

Purpose of the Study:

  • To highlight the significant proportion of preterm births represented by MPT and LPT infants.
  • To underscore the increased risk of adverse neurodevelopmental and behavioral outcomes in these populations.

Main Methods:

  • Analysis of population data on preterm births.
  • Review of existing evidence on infant outcomes based on gestational age.

Main Results:

  • MPT and LPT infants represent the largest subgroup of preterm infants in the US.
  • A dose-response relationship exists between decreased gestational age (below 39 weeks) and increased adverse outcomes.

Conclusions:

  • MPT and LPT infants are a vulnerable population requiring close monitoring.
  • Gestational age is a critical factor influencing long-term infant health and development.

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