Jove
Visualize
Contact Us

Related Concept Videos

Hierarchy of Motor Control01:18

Hierarchy of Motor Control

5.6K
The hierarchy of motor control refers to the different levels of organization and processing involved in controlling movement in the body. These levels range from higher cortical areas involved in planning and decision-making to lower spinal cord reflexes that respond automatically to external stimuli.
5.6K
Electro-mechanical Systems01:19

Electro-mechanical Systems

1.3K
Electromechanical systems are intricate configurations that effectively combine electrical and mechanical elements to achieve a desired outcome. Central to many of these systems is the DC motor, a device that converts electrical energy into mechanical motion, enabling various applications ranging from simple fans to complex robotic mechanisms.
A key component of the DC motor is the armature, a rotating circuit positioned within a magnetic field. As an electric current passes through the...
1.3K
Indirect Motor Pathways01:22

Indirect Motor Pathways

3.4K
The indirect motor or extrapyramidal pathways originate in the brainstem, the lower portion of the brain that connects it to the spinal cord. They consist of several distinct tracts, each with specialized functions. The four main tracts of the indirect motor pathways are the vestibulospinal tract, the reticulospinal tract, the tectospinal tract, and the rubrospinal tract.
The vestibulospinal tract originates in the vestibular nuclei of the brainstem. The vestibular system detects changes in...
3.4K
Direct Motor Pathways01:11

Direct Motor Pathways

4.7K
The direct motor pathways, also known as the pyramidal tracts, are a group of neural pathways that originate in the brain and descend through the spinal cord. They control the voluntary movement of the body. There are two major direct motor pathways: the corticospinal and the corticobulbar tracts.
The corticospinal tract is responsible for the voluntary movement of the limbs and trunk. It originates in the cerebral cortex of the brain and descends through the cerebrum's internal capsule and...
4.7K
Enteric Nervous System: Regulation of GI Motor Activity01:11

Enteric Nervous System: Regulation of GI Motor Activity

2.2K
The Enteric Nervous System (ENS) plays a pivotal role in regulating gastrointestinal or GI motor activity. This complex network of nerves, deeply embedded within the gut wall, responds to changes in the gut environment and receives input from both the autonomic nervous system and the central nervous system. By doing so, the ENS operates various programs tailored to the body's nutritional status and needs.
During periods of fasting, the ENS initiates the migrating myoelectric complex, a...
2.2K
Motor Unit Stimulation01:20

Motor Unit Stimulation

4.7K
When the neuron of a motor unit fires an action potential, it triggers a series of events, leading to a twitch contraction in the muscle fibers. The process of excitation-contraction coupling is crucial in relaying the action potential to the muscle fibers.
The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...
4.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Adaptive Charge Modulation Enables Focal, Selective Spinal Cord Stimulation.

bioRxiv : the preprint server for biology·2026
Same author

Multi-area activity in mouse motor cortex associated with one- and two-handed oromanual dexterity.

bioRxiv : the preprint server for biology·2026
Same author

A brain-wide, trial- and time-dependent deterministic drive synergizes with within-trial noise to time self-initiated actions.

bioRxiv : the preprint server for biology·2026
Same author

Potentiation of active locomotor state by spinal-projecting serotonergic neurons.

Neuron·2026
Same author

Directed differentiation of functional corticospinal-like neurons from endogenous SOX6+/NG2+ cortical progenitors.

eLife·2026
Same author

Prospective isolation of mouse and human hematopoietic stem cells using PLXDC2.

Communications biology·2025
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 6, 2026

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface
11:54

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface

Published on: May 8, 2021

4.2K

Edging toward entelechy in motor control.

Andrew Miri1, Eiman Azim, Thomas M Jessell

  • 1Departments of Neuroscience and Biochemistry and Molecular Biophysics, Howard Hughes Medical Institute, Zuckerman Mind Brain Behavior Institute, and Kavli Institute for Brain Science, Columbia University, New York, NY 10032, USA.

Neuron
|November 5, 2013
PubMed
Summary

Understanding corticospinal motor neuron (CMN) connections is key to deciphering movement control. This essay proposes focusing on cortical and spinal circuit intersections to clarify CMN function and firing patterns.

More Related Videos

In Vivo Wireless Optogenetic Control of Skilled Motor Behavior
07:52

In Vivo Wireless Optogenetic Control of Skilled Motor Behavior

Published on: November 22, 2021

3.1K
WheelCon: A Wheel Control-Based Gaming Platform for Studying Human Sensorimotor Control
08:18

WheelCon: A Wheel Control-Based Gaming Platform for Studying Human Sensorimotor Control

Published on: August 15, 2020

4.3K

Related Experiment Videos

Last Updated: May 6, 2026

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface
11:54

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface

Published on: May 8, 2021

4.2K
In Vivo Wireless Optogenetic Control of Skilled Motor Behavior
07:52

In Vivo Wireless Optogenetic Control of Skilled Motor Behavior

Published on: November 22, 2021

3.1K
WheelCon: A Wheel Control-Based Gaming Platform for Studying Human Sensorimotor Control
08:18

WheelCon: A Wheel Control-Based Gaming Platform for Studying Human Sensorimotor Control

Published on: August 15, 2020

4.3K

Area of Science:

  • Neuroscience
  • Motor Control
  • Computational Neuroscience

Background:

  • The precise organization and functional logic of corticospinal motor neurons (CMNs) and their connections are not fully understood, hindering our comprehension of movement.
  • Spinal interneurons play a crucial role in mediating CMN influence on movement, but the mechanisms by which CMNs engage these interneurons remain largely unknown.
  • The intricate organization of local spinal microcircuits lacks a comprehensive functional architecture, making it difficult to interpret CMN activity.

Purpose of the Study:

  • To advocate for a novel research approach focusing on the interplay between cortical and spinal circuits.
  • To provide a framework for interpreting corticospinal motor neuron firing patterns.
  • To elucidate the functional logic governing corticospinal motor neuronal activity.

Main Methods:

  • This is a conceptual essay, not an experimental study.
  • It synthesizes existing knowledge on corticospinal and spinal circuits.
  • It proposes a new perspective for future research.

Main Results:

  • A clear understanding of CMN organization and function is currently lacking.
  • The interaction between CMNs and spinal interneurons is poorly understood.
  • The functional architecture of spinal microcircuits remains elusive.

Conclusions:

  • A renewed focus on the intersection of cortical and spinal circuits is essential.
  • This approach promises to clarify the interpretation of CMN firing patterns.
  • Investigating this intersection will advance our understanding of corticospinal motor neuronal function.