Related Experiment Video
Updated: May 6, 2026
10:10
Quantifying Cognitive Decrements Caused by Cranial Radiotherapy
Published on: October 18, 2011
13.5K
Cognitive changes associated with central nervous system malignancies and treatment
Seminars in Oncology Nursing
|November 5, 2013
Summary
Brain tumors and their treatments can cause cognitive decline, impacting patient quality of life. Neuro-oncology nurses play a key role in managing these cognitive impairments for patients and caregivers.
Area of Science:
- Neuro-oncology
- Cognitive Neuroscience
- Oncology Nursing
Background:
- Central nervous system (CNS) malignancies are increasingly survivable due to therapeutic advancements.
- Despite improved survival, cognitive deficits remain a significant challenge for patients with brain tumors.
- These cognitive changes negatively affect patient quality of life and caregiver well-being.
Purpose of the Study:
- To review cognitive changes associated with infiltrative malignant brain tumors.
- To examine cognitive sequelae resulting from brain tumor treatments.
- To highlight the role of neuro-oncology nurses in managing these cognitive impairments.
Main Methods:
- Comprehensive review of existing journal articles.
- Synthesis of information from relevant textbooks.
Main Results:
- Therapeutic improvements in CNS malignancies correlate with increased survival rates.
- Both the presence of brain tumors and their treatment modalities are linked to cognitive decline.
- Cognitive impairments contribute to a diminished quality of life and increased caregiver burden.
Conclusions:
- Neuro-oncology nurses are crucial in identifying cognitive impairments and implementing strategies to enhance patient and caregiver quality of life.
- Future research aims to further optimize treatments, minimize side effects, and reduce cognitive deficits associated with brain tumors and their therapies.
- Reducing cognitive sequelae is a primary long-term objective for the neuro-oncology community.
More Related Videos
Related Concept Videos
02:56Treatment Resistant Cancers
2.7K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
2.7K
02:49Cancer Therapies
8.6K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
8.6K
01:28Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists
829
Neurokinin 1 (NK1) receptors are distributed across the GI tract, vagal afferents, and key CNS regions including the central vomiting center and chemoreceptor trigger zone (CTZ) Chemotherapy agents stimulate enterochromaffin cells in the gastrointestinal (GI) tract to release large amounts of substance P (SP). SP is a neuropeptide released by specific sensory nerves in response to many different stressors, including those in the GI mucosa affected by chemotherapy. SP binds and activates...
829
02:56Treatment Resistent Cancers
1.1K
1.1K
01:29Chemotherapy-Induced Nausea and Vomiting: Dopamine Receptor Antagonists
1.2K
Dopamine receptor antagonists, also known as antipsychotic agents, are critical in managing chemotherapy-induced vomiting. These antiemetic agents block dopamine receptors in the chemoreceptor trigger zone (CTZ), inhibiting signal transmission to the vomiting center. Antipsychotic agents encompass phenothiazines (PTZ), butyrophenones, benzamides, and thienobenzodiazepines (Zyprexa), which are utilized for their antiemetic and sedative properties.
Phenothiazines, such as prochlorperazine...
Phenothiazines, such as prochlorperazine...
1.2K
01:19Psychoneuroimmunology: Diabetes and Cancer
536
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
536