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Dynorphin/KOP and nociceptin/NOP gene expression and epigenetic changes by cocaine in rat striatum and nucleus

Francesca Felicia Caputi1, Manuela Di Benedetto1, Donatella Carretta1

  • 1Department of Pharmacy and Biotechnologies, Alma Mater Studiorum, University of Bologna, Irnerio 48, 40126 Bologna, Italy.

Progress in Neuro-Psychopharmacology & Biological Psychiatry
|November 5, 2013
PubMed

Keywords:
CPuChIPCocaineDOPDYNEpigeneticH3K27me3H3K4me3KOPMOPN/OFQNANOPProdynorphinPronociceptinRT-qPCRRatcaudate-putamenchromatin immunoprecipitationdelta-opioid receptordynorphinkappa-opioid receptorlCPulateral caudate-putamenmCPumedial caudate-putamenmu-opioid receptornociceptinnucleus accumbensorphaninFQ-nociceptin receptorreal-time quantitative polymerase chain reactiontrimethylation of H3 at Lys27trimethylation of H3 at Lys4 level

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