Related Experiment Video

Updated: May 6, 2026

Protocol for Isolating the Mouse Circle of Willis
06:30

Protocol for Isolating the Mouse Circle of Willis

Published on: October 22, 2016

12.7K

Circle of Willis in adults

S M Al-Hussain1, A M Shoter, Z M Bataina

  • 1Department of Anatomy, Jordan University of Science and Technology, Irbid, Jordan.

Neurosciences (Riyadh, Saudi Arabia)
|November 5, 2013
PubMed

Insights

Variations in the Circle of Willis are common, with 14 types identified, including a novel one. Understanding these anatomical differences is crucial for diagnosing and treating brain artery obstructions.

Area of Science:

  • Neuroanatomy
  • Vascular Neurology

Background:

  • The Circle of Willis is a critical arterial anastomosis at the base of the brain.
  • Anatomical variations in the Circle of Willis are frequently encountered.

Purpose of the Study:

  • To document the primary variations of the Circle of Willis.
  • To elucidate the clinical significance of these anatomical variations.

Main Methods:

  • Analysis of 50 adult Jordanian Circles of Willis.
  • Detailed arterial drawing and measurement using a stereoscopic microscope.

Main Results:

  • Identification of 14 distinct Circle of Willis configurations.
  • 13 variations align with previously described types; one is novel.
  • Detailed description of the diversity and frequency of variations observed.

Conclusions:

  • Anatomical variations of the Circle of Willis are highly prevalent.
  • These variations can significantly impact the presentation and management of cerebrovascular diseases.
Abstract

More Related Videos

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis09:36

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis

Published on: August 12, 2025

844
Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA13:10

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA

Published on: April 24, 2017

17.7K

Related Concept Videos

The Arch of Aorta01:10

The Arch of Aorta

The coronary arteries, originating from the ascending aorta, bifurcate from two sinuses located within the ascending aorta. Positioned just above the aortic semilunar valve, these sinuses house essential aortic baroreceptors and chemoreceptors, crucial for maintaining cardiac function. The left coronary artery and the right coronary artery branch off from the left posterior and anterior aortic sinuses, respectively.
Encircling the heart, the coronary arteries form a ring-like structure before...
2.2K
Arteries of the Head and Neck01:26

Arteries of the Head and Neck

The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
4.3K
Spinal Cord: Gross Anatomy01:15

Spinal Cord: Gross Anatomy

The spinal cord resides within the protective confines of the vertebral column. It is the main pathway for information traveling between the brain and the body. It plays a fundamental role in nearly all bodily functions, from simple reflexes to complex motor movements. The spinal cord begins at the medulla oblongata at the base of the brainstem and extends downward, terminating at the conus medullaris near the first and second lumbar vertebrae. The spinal cord's length in adults is...
6.4K
Anatomy of the Brain: Major Regions01:20

Anatomy of the Brain: Major Regions

The brain is the most complex organ in the human body. It consists of four main parts: the cerebrum, diencephalon, cerebellum, and brainstem.
The cerebrum is the largest section of the brain and divides into left and right hemispheres, separated by a deep fissure. The cerebral outer layer of grey matter — the cerebral cortex — comprises elevations called gyri and shallow groves called sulci. The inner portion of white matter includes long nerve fibers known as axons, which connect...
11.6K
The Spinal Cord01:54

The Spinal Cord

The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
27.5K
Brainstem01:19

Brainstem

The brainstem, located inferior to the brain and superior to the spinal cord, serves as a bridge between the cerebrum and the spinal cord. It plays a vital role in relaying information and controlling critical life functions. It comprises three primary regions: the midbrain, pons, and medulla oblongata.
The Midbrain
The midbrain is located beneath the diencephalon and connects the cerebrum with the lower parts of the brain. The cerebral peduncles are prominent midbrain structures that house the...
7.5K