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Updated: May 6, 2026

A Mouse Model for Vascular Cognitive Impairment and Dementia Based on Needle-guided Asymmetric Bilateral Common Carotid Artery Stenosis
Published on: November 22, 2024
Neurobehavioral effects of carotid endarterectomy
H M Rabee1, M K Saadani, K M Iqbal
1Vascular Surgery Division, Department of Surgery (37), King Khalid University Hospital, PO Box 7805, Riyadh 11472, Kingdom of Saudi Arabia. Tel. +966 (1) 467 1589, Fax. +966 (1) 467 9493,
Objective:
Nineteen patients with symptomatic carotid stenosis (>70%) were subjected to carotid endarterectomy in a prospective study to evaluate neurobehavioral changes before and 6 months following the operation.
Methods:
All patients were subjected to neurobehavioral rating scale one week before and 6 months after the operation.
Results:
There were no significant changes in the 27 items of this scale before and 6 months following the operation. Some patients showed no difference at all in some items of this scale before and after operation such as suspiciousness excitement, speech and articulation using Mann-Whitney rank test, P values were (> 0.05) as regards to all items of neurobehavioral rating scale.
Conclusion:
Uncomplicated carotid endarterectomy does not seem to be associated with significant long time neurobehavioral impairment following the operation.
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