Related Experiment Video
Updated: May 6, 2026

03:38
Aptamer-Based Target Detection Facilitated by a 3-Stage G-Quadruplex Isothermal Exponential Amplification Reaction
Published on: October 6, 2022
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An ultra-sensitive colorimetric detection of tetracyclines using the shortest aptamer with highly enhanced affinity
Young Seop Kwon1, Nurul Hanun Ahmad Raston, Man Bock Gu
1School of Life Sciences and Biotechnology, Korea University, Anam-dong, Seongbuk-Gu, Seoul 136-713, Republic of Korea. mbgu@korea.ac.kr.
Abstract:
A shortened 8-mer ssDNA aptamer was successfully truncated for four different tetracyclines with high affinity. The ultrasensitive colorimetric detection of oxytetracycline using this shortened aptamer was possible, which was about 500-fold enhanced compared to that obtained using the original 76-mer aptamer.

