Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bioplastics01:27

Bioplastics

73
Bioplastics derived from microbial processes present a sustainable alternative to conventional petroleum-based plastics. Among these, polyhydroxyalkanoates (PHAs), particularly polyhydroxybutyrates (PHBs), have emerged as prominent candidates due to their biodegradability and biocompatibility. These polymers are synthesized by a variety of bacteria, such as Cupriavidus necator and Pseudomonas putida, which naturally accumulate PHAs as intracellular carbon and energy reserves, especially under...
73
Teratogenicity01:07

Teratogenicity

4.2K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
4.2K
Gonadal and Placental Hormones01:24

Gonadal and Placental Hormones

3.9K
The gonads, namely the testes in males and the ovaries in females, are pivotal in producing gonadal hormones that orchestrate the intricate processes of sexual development and reproduction.
In males, testosterone is the primary gonadal androgen. It plays a central role in the maturation of male reproductive organs — the penis and testes. Additionally, testosterone is instrumental in the development of secondary sexual characteristics — a deep voice as well as facial and pubic hair...
3.9K
Factors Affecting Drug Biotransformation: Biological01:19

Factors Affecting Drug Biotransformation: Biological

925
Biological factors significantly impact drug metabolism, influencing drug clearance, efficacy, and potential toxicity.
Species differences: Variations in enzyme systems across species can cause disparities in drug metabolism. For instance, humans may metabolize certain drugs faster than rodents, altering therapeutic effects.
Strain differences: Genetic variations within a species can result in differing enzyme activity, impacting drug response and toxicity. For example, some mouse strains may...
925

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Maternal and fetal HLA heterozygosity in preeclampsia: Insights from a large multi-ancestry pregnancy cohort.

medRxiv : the preprint server for health sciences·2026
Same author

Handling of multicohort data in pooled analysis of environmental exposures: confounding by cohort of the relationship between perfluoroalkyl substances and birthweight in the ECHO Program.

American journal of epidemiology·2026
Same author

Evaluation of integrated, multimedia biomarkers of prenatal metals exposure in association with child neurodevelopment in Puerto Rico.

Journal of exposure science & environmental epidemiology·2026
Same author

Prenatal phthalate exposure and emotional-behavioral problems in children aged 1.5 to 3 years from the PROTECT birth cohort.

Journal of exposure science & environmental epidemiology·2026
Same author

Prenatal over-the-counter acetaminophen use and birth outcomes in the ECHO cohort.

American journal of epidemiology·2026
Same author

Associations of per- and polyfluoroalkyl substances (PFAS) exposure and thyroid hormone concentration during pregnancy in the LIFECODES cohort.

International journal of hygiene and environmental health·2026
Same journal

Optimizing technology for cervical cancer screening in high-resource settings.

Expert review of obstetrics & gynecology·2015
Same journal

Modulating the tumor immune microenvironment as an ovarian cancer treatment strategy.

Expert review of obstetrics & gynecology·2013
Same journal

The role of reproductive hormones in the development and maintenance of eating disorders.

Expert review of obstetrics & gynecology·2013
Same journal

Animal models of female pelvic organ prolapse: lessons learned.

Expert review of obstetrics & gynecology·2012
Same journal

Reproductive coercion and partner violence: implications for clinical assessment of unintended pregnancy.

Expert review of obstetrics & gynecology·2012
Same journal

Lack of evidence for prescription of antepartum bed rest.

Expert review of obstetrics & gynecology·2011
See all related articles

Related Experiment Video

Updated: May 6, 2026

Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants
07:08

Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants

Published on: March 6, 2018

8.1K

Bisphenol A and Human Reproductive Health.

David E Cantonwine1, Russ Hauser, John D Meeker

  • 1Department of Environmental Health Sciences University of Michigan School of Public Health Ann Arbor, MI 48109, USA.

Expert Review of Obstetrics & Gynecology
|November 5, 2013
PubMed
Summary
This summary is machine-generated.

Bisphenol A (BPA) exposure may harm human reproduction and pregnancy. This review summarizes research on BPA

Keywords:
BPAbirth weightepidemiologyfertilityhumanpregnancypreterm birthreproductive health

More Related Videos

Assessment of the Effects of Endocrine Disrupting Compounds on the Development of Vertebrate Neural Network Function Using Multi-electrode Arrays
08:28

Assessment of the Effects of Endocrine Disrupting Compounds on the Development of Vertebrate Neural Network Function Using Multi-electrode Arrays

Published on: April 26, 2018

8.8K
A Murine Pancreatic Islet Cell-based Screening for Diabetogenic Environmental Chemicals
07:39

A Murine Pancreatic Islet Cell-based Screening for Diabetogenic Environmental Chemicals

Published on: June 25, 2018

6.8K

Related Experiment Videos

Last Updated: May 6, 2026

Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants
07:08

Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants

Published on: March 6, 2018

8.1K
Assessment of the Effects of Endocrine Disrupting Compounds on the Development of Vertebrate Neural Network Function Using Multi-electrode Arrays
08:28

Assessment of the Effects of Endocrine Disrupting Compounds on the Development of Vertebrate Neural Network Function Using Multi-electrode Arrays

Published on: April 26, 2018

8.8K
A Murine Pancreatic Islet Cell-based Screening for Diabetogenic Environmental Chemicals
07:39

A Murine Pancreatic Islet Cell-based Screening for Diabetogenic Environmental Chemicals

Published on: June 25, 2018

6.8K

Area of Science:

  • Environmental Health
  • Reproductive Toxicology
  • Epidemiology

Background:

  • Bisphenol A (BPA) is a widely produced chemical.
  • Toxicological studies indicate adverse endocrine and reproductive effects.
  • Human data on BPA's reproductive and pregnancy impacts are limited.

Purpose of the Study:

  • To review epidemiological literature on BPA and human fertility.
  • To examine the association between BPA exposure and adverse pregnancy outcomes.
  • To provide resources for healthcare providers on reducing BPA exposure.

Main Methods:

  • Systematic review of epidemiological studies.
  • Literature search for studies on BPA exposure, fertility, and pregnancy outcomes.
  • Synthesis of current evidence on human health effects.

Main Results:

  • Evidence suggests potential adverse effects of BPA on human fertility.
  • Associations found between BPA exposure and certain adverse pregnancy outcomes.
  • Further research is needed to fully elucidate human health impacts.

Conclusions:

  • Bisphenol A is an endocrine-disrupting chemical with potential risks to human reproduction and pregnancy.
  • Healthcare providers can play a role in educating patients and reducing exposure.
  • Public health strategies may be needed to mitigate BPA-related risks.