Related Experiment Video

Updated: May 6, 2026

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
08:46

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

5.5K

Salmonella enterica Serotype Arizonae Meningitis in a Neonate

Wubishet Lakew1, Abayneh Girma, Elizabeth Triche

  • 1Department of Pediatrics and Child Health, University of Gondar, 196 Gondar, Ethiopia.

Case Reports in Pediatrics
|November 5, 2013
PubMed

Insights

Salmonella enterica serotype Arizonae rarely causes meningitis. This case highlights its potential in neonates, emphasizing its inclusion in the differential diagnosis for Gram-negative bacillary meningitis in infants.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Neonatal Medicine

Background:

  • Salmonella species are common causes of gastroenteritis.
  • Invasive Salmonella infections, such as meningitis, are rare.
  • Salmonella enterica serotype Arizonae is an uncommon cause of human infection.

Purpose of the Study:

  • To report the first case of Salmonella enterica serotype Arizonae meningitis in a neonate.
  • To highlight the clinical presentation and outcome of this rare infection.
  • To emphasize the importance of considering this pathogen in neonatal meningitis.

Main Methods:

  • Case report of a 13-day-old female neonate presenting with meningitis symptoms.
  • Cerebrospinal fluid (CSF) culture to identify the causative agent.
  • Clinical management and monitoring of treatment response.

Main Results:

  • Cerebrospinal fluid (CSF) culture identified Salmonella enterica serotype Arizonae.
  • The neonate developed severe complications including hydrocephalus and seizures.
  • Despite treatment, the infant succumbed to the infection after two weeks of hospitalization.

Conclusions:

  • Salmonella enterica serotype Arizonae is a rare but serious cause of neonatal meningitis.
  • This serotype should be considered in the differential diagnosis of Gram-negative bacillary meningitis in neonates, especially those with reptile exposure.
  • Early recognition and appropriate antibiotic therapy are crucial, though outcomes can be poor.

More Related Videos

Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat08:27

Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat

Published on: October 29, 2014

13.1K
Oral Transmission of Listeria monocytogenes in Mice via Ingestion of Contaminated Food08:38

Oral Transmission of Listeria monocytogenes in Mice via Ingestion of Contaminated Food

Published on: May 6, 2013

18.8K

Related Concept Videos

Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
32
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
219
Reservoir of Infection01:30

Reservoir of Infection

Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...
110
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
29
Arboviral Encephalitis01:25

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
70
Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid...
95