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Coeliac disease is more common in children with high socio-economic status

L A Whyte1, S Kotecha, W J Watkins

  • 1Department of Paediatric Gastroenterology, Children's Hospital of Wales, Cardiff, UK.

Acta Paediatrica (Oslo, Norway : 1992)
|November 6, 2013
PubMed

Insights

Coeliac disease prevalence was higher in children from affluent areas, suggesting socio-economic status influences risk. Further research is needed to understand these associations.

Area of Science:

  • Paediatric gastroenterology
  • Epidemiology
  • Genetics

Background:

  • Coeliac disease (an autoimmune disorder) has complex risk factors, including genetic and environmental influences.
  • The relationship between socio-economic status (SES) and coeliac disease development requires further investigation.

Purpose of the Study:

  • To investigate the association between socio-economic deprivation and the incidence of coeliac disease in children.
  • To determine if SES impacts the risk of developing coeliac disease.

Main Methods:

  • A cross-sectional study analyzed data from 232 children diagnosed with coeliac disease (<16 years) between 1995 and 2011.
  • Patient postcodes were linked to the Welsh Index of Multiple Deprivation (WIMD) score to assess socio-economic status.

Main Results:

  • A graded association was observed between coeliac disease prevalence and socio-economic deprivation.
  • Children residing in more affluent areas exhibited a higher prevalence of coeliac disease (rate/1000 = 1.16) compared to those in the most deprived areas (rate/1000 = 0.49).

Conclusions:

  • Coeliac disease was found to be more prevalent in children from higher socio-economic groupings within the studied population.
  • Potential contributing factors include the 'hygiene hypothesis' and parental health-seeking behaviors associated with higher SES.
Abstract

Keywords:
DeprivationEpidemiologyGastroenterologyGeneral paediatricsSocio-economic status

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