Adult genetic risk screening
C Thomas Caskey1, Manuel L Gonzalez-Garay, Stacey Pereira
1Department of Molecular and Human Genetics.
Annual Review of Medicine
|November 6, 2013
Summary
Genetic screening using DNA sequencing offers a new strategy for adult disease prevention. Expanding genetic risk identification can reduce adult-onset disease incidence through early intervention.
Area of Science:
- Genetics
- Preventive Medicine
- Genomic Medicine
Background:
- Current medical practice often prioritizes disease pathology over prevention.
- Genetic screening has proven effective for childhood diseases and newborn care.
- There is a significant opportunity to apply genetic screening to adult-onset diseases.
Purpose of the Study:
- To explore the potential of genetic screening for adult disease prevention.
- To outline strategies for implementing genetic risk identification in adults.
- To discuss the challenges and benefits of adult genetic screening programs.
Main Methods:
- Review of recent advances in DNA sequencing technology.
- Analysis of current approaches to disease prevention and genetic screening.
- Conceptual framework for expanding genetic screening to adult populations.
Main Results:
- Advances in genetic analysis enable new strategies for disease risk identification.
- Genetic screening can shift focus from treatment to proactive prevention.
- Expansion of screening can lead to reduced incidence of adult-onset conditions.
Conclusions:
- Genetic screening holds significant promise for the prevention of adult-onset diseases.
- Proactive genetic risk identification and intervention are crucial for public health.
- Further development and implementation of adult genetic screening programs are warranted.
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