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Updated: May 6, 2026

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
Published on: March 16, 2022
Preliminary experiences with early primary closure of foot wounds after lower extremity revascularization
Neal R Barshes1, Carlos F Bechara1, George Pisimisis1
1Division of Vascular Surgery and Endovascular Therapy, Michael E. DeBakey Department of Surgery, Baylor College of Medicine/Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX.
Background:
The costs associated with local wound care after revascularization can be significant, and it has been suggested that early closure or healing of foot wounds can be a source of cost savings. We sought to determine the safety and effectiveness of attempts to primarily close chronic foot wounds early after revascularization.
Methods:
We performed a single-center 1-year review of patients who underwent primary wound closure during the same hospitalization as revascularization.
Results:
Seven patients underwent an attempt at early primary wound closure. Most (71%) were diabetic. The wounds were primarily closed at a median of 6 days after revascularization (range 3-8 days). The limb-salvage rate at 6 months was 86%. Four patients remained completely healed with primary closure. One healed secondarily with wound care, and 2 required major amputation. Wound-closure techniques included the use of toe/forefoot amputations, skin grafting, and local flaps.
Conclusions:
Early primary closure after revascularization may be a safe technique to consider for carefully selected foot wounds without ongoing soft tissue infection.
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