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Paediatric oral biopharmaceutics: key considerations and current challenges

Hannah K Batchelor1, Nikoletta Fotaki2, Sandra Klein3

  • 1Pharmacy, Pharmacology and Therapeutics Section, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, Medical School Building, University of Birmingham, Edgbaston B15 2TT, United Kingdom.

Advanced Drug Delivery Reviews
|November 6, 2013
PubMed
Summary

Developing effective pediatric drug formulations requires specialized biopharmaceutical tools. Current methods for adults need adaptation for children, especially neonates and infants, due to significant gastrointestinal differences.

Keywords:
DissolutionMetabolismPermeabilityPhysiologically based pharmacokinetic modellingSolubility

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