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Related Experiment Video

Updated: May 6, 2026

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Predicting functional decline in older patients undergoing cardiac surgery.

Jita G Hoogerduijn1, Sophia E de Rooij, Diederick E Grobbee

  • 1University of Applied Sciences Utrecht, Utrecht, Netherlands.

Age and Ageing
|November 6, 2013
PubMed
Summary
This summary is machine-generated.

An updated tool, the Identification of Seniors at Risk-Hospitalised Patients (ISAR-HP), effectively predicts functional decline in older adults after cardiac surgery. This helps identify at-risk patients for targeted interventions.

Keywords:
ISAR-HPcardiac surgeryfunctional declineolder patientolder peopleprediction

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Area of Science:

  • Geriatric Medicine
  • Cardiovascular Surgery
  • Health Outcomes Research

Background:

  • Older adults undergoing cardiac surgery face a high risk of post-operative functional decline.
  • This decline can significantly impair quality of life, autonomy, and lead to adverse health outcomes.
  • Currently, no validated tools exist to predict this functional decline in cardiac surgery patients.

Purpose of the Study:

  • To validate the Identification of Seniors at Risk-Hospitalised Patients (ISAR-HP) tool for predicting functional decline in elderly patients undergoing cardiac surgery.
  • To assess the generalizability of the ISAR-HP tool in this specific patient population.

Main Methods:

  • A multicenter cohort study involving consecutive cardiac surgery patients aged 65 and older.
  • Functional decline was defined as a ≥1 point decrease on the Katz ADL Index at 3-month follow-up.
  • An amended ISAR-HP prediction model was developed and validated.

Main Results:

  • 475 patients were included; 16% experienced functional decline (20% in those ≥70).
  • The amended ISAR-HP identified four key predictors: preadmission assistance needs, walking device use, travel assistance, and limited education.
  • The model demonstrated good discriminative ability (AUC 0.73 for ≥70 group) with high sensitivity (85%) and negative predictive value (93%).

Conclusions:

  • The amended ISAR-HP tool shows good discriminative value for predicting functional decline in older cardiac surgery patients.
  • The findings support the tool's generalizability and utility for identifying at-risk individuals in this population.
  • Early identification enables targeted preventive strategies to mitigate functional decline and improve patient outcomes.