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Published on: June 23, 2020
[Surgical site infection: risk factors, prevention, diagnosis and treatment]
C Di Benedetto1, A Bruno, E Bernasconi
1Servizio Malattie Infettive (Service des maladies infectieuses), Ospedale Civico Lugano, Via Tesserete 46, 6900 Lugano. caroline.dibenedetto@eoc.ch
Abstract:
Surgical site infection comprises the cutaneous tissues until the intraabdominal or pleural cavity. The infectious risk depends on the degree of bacterial contamination, the general conditions of the patient and procedure-related factors. The causal microbes originate from the flora of the skin or the mucosal surfaces that have been touched during the operation. Superficial non-complicated infections are treated locally. However, an infected surgical wound can be the top of a deep infection. Infections with foreign material underneath deserve particular attention. Empiric antibiotic therapy is prohibited in these cases. Treatment is normally a combination of surgical debridement and specific antimicrobial therapy.
Insights
Surgical site infections (SSIs) range from skin to deep cavities, influenced by contamination and patient factors. Treatment involves surgical debridement and targeted antibiotics, avoiding empiric therapy, especially with foreign materials.
Area of Science:
- Infectious Diseases
- Surgical Infections
- Microbiology
Context:
- Surgical site infections (SSIs) are a significant concern in healthcare settings.
- Understanding the sources and risk factors for SSIs is crucial for prevention and management.
- The spectrum of SSIs ranges from superficial cutaneous infections to deep infections involving body cavities.
Purpose:
- To outline the etiology, risk factors, and management strategies for surgical site infections.
- To differentiate between superficial and deep SSIs and their respective treatment approaches.
- To emphasize the importance of avoiding empiric antibiotic therapy in specific SSI cases.
Summary:
- SSIs involve contamination of surgical wounds by endogenous microbial flora.
- Infection risk is multifactorial, including bacterial load, patient health, and surgical procedure details.
- Superficial SSIs are managed locally, while deep SSIs, particularly those with foreign material, require aggressive surgical debridement and specific antimicrobial treatment.
- Empiric antibiotic therapy is contraindicated in cases with foreign material due to potential complications.
Impact:
- Improved understanding of SSI pathogenesis and risk stratification.
- Guidance on appropriate treatment strategies, emphasizing debridement and targeted therapy.
- Reduced incidence of complications associated with inappropriate antibiotic use in SSIs.
- Enhanced patient outcomes through effective management of surgical wound infections.
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