Related Experiment Video
Updated: May 6, 2026

A Novel Ex Ovo Banding Technique to Alter Intracardiac Hemodynamics in an Embryonic Chicken System
Published on: May 13, 2016
[Agenesis of the ductus venosus--an irrelevant anomaly or a severe clinical problem?]
Wojciech Cnota1, Agata Włoch, Bartosz Czuba
1Oddział Kliniczny Połoznictwa i Ginekologii w Rudzie Slaskiej, Slaski Uniwersytet Medyczny, Polska. woytek@eth.pl
Insights
Agenesis of the ductus venosus, a vital fetal blood vessel, can lead to severe complications like intrauterine death. However, fetuses without other anomalies often have a good prognosis with proper monitoring.
Area of Science:
- Fetal Medicine
- Perinatology
- Cardiovascular Physiology
Background:
- The ductus venosus is a critical fetal blood vessel connecting the umbilical vein to the inferior vena cava.
- Its role in fetal circulation is well-established.
- Identifying the ductus venosus during ultrasound is not always possible.
Purpose of the Study:
- To evaluate the outcomes of fetuses diagnosed with agenesis (absence) of the ductus venosus.
- To assess the severity and impact of ductus venosus agenesis during fetal development.
Main Methods:
- A cohort of 17 fetuses from singleton pregnancies with confirmed ductus venosus agenesis was prospectively followed.
- Clinical data and ultrasound findings were systematically collected and analyzed.
Main Results:
- Three intrauterine deaths occurred, associated with fetal hydrops and heart failure.
- One neonate required postnatal cardiac intervention.
- Most cases of isolated ductus venosus agenesis (without other developmental issues) showed a favorable prognosis.
Conclusions:
- Fetal agenesis of the ductus venosus necessitates specialized care in referral centers.
- Prompt diagnosis and management are crucial for optimizing fetal and neonatal outcomes.
Background:
Ductus venosus is the fetal blood vessel connecting the abdominal portion of the umbilical vein with the inferior vena cava. Numerous studies have confirmed the important role of this vessel in fetal circulation. There are, however cases when finding the ductus venosus during an ultrasound examination is impossible.
Objective:
The objective of the study was to assess the fate of fetuses with known ductus venosus agenesis and its severity in fetal life.
Material And Methods:
17 fetuses from singleton pregnancies with agenesis of the ductus venosus were observed and followed up.
Results:
A total of 3 intrauterine deaths, preceded by fetal hydrops and signs of heart failure, were observed in the study group. One newborn required cardiac care after birth. In the majority of cases with ductus venosus agenesis, where no accompanying developmental anomalies were found, prognosis for the fetus and the newborn was good.
Conclusions:
Cases of ductus venosus agenesis should be directed to and followed up in referral centers, where adequate diagnostic and therapeutic procedures can be undertaken.
Related Concept Videos
Fetal Circulation
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Development of Blood Vessels
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
Varicose Veins I: Introduction
Veins of the Abdomen and Pelvis
The inferior vena cava is fed by numerous smaller veins. The lumbar veins, for instance, drain the posterior abdominal wall, emptying both directly into the inferior vena cava and into the...
Development of the Heart
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart...
Overview of Systemic Veins
The coronary sinus, the heart's principal vein, resides in the coronary sulcus on the heart's posterior aspect. This broad venous channel receives nearly all venous blood from the myocardium, the heart muscle. It is fed by three primary veins: the great cardiac vein, the...

