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Autoantigens: novel forms and presentation to the immune system

Hester A Doyle1, Mei-Ling Yang, Maurice T Raycroft

  • 1Section of Rheumatology, Department of Internal Medicine, Yale University School of Medicine , New Haven, CT , USA.

Autoimmunity
|November 7, 2013
PubMed
Summary

Lupus autoimmunity involves genetic, epigenetic, and environmental factors. This review focuses on non-genetic influences like protein post-translational modifications (PTMs) and autoantigen presentation in lupus pathogenesis and diagnosis.

Keywords:
Antigen presentationantigen presenting cellsdiagnosticsmethylationpost-translational modification

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