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Related Experiment Video

Updated: May 6, 2026

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy

Published on: August 22, 2025

Vacuum sealing: indication, technique, and results.

W Fleischmann¹, U Becker, M Bischoff

¹Abteilung für Unfallchirurgie, Hand-, Plastische und Wiederherstellungschirurgie, Universität Ulm, Steinhövelstrasse 9, D-89075, Ulm, Germany.

European Journal of Orthopaedic Surgery & Traumatology : Orthopedie Traumatologie

|November 7, 2013

Summary

Vacuum sealing therapy offers rapid wound healing for traumatic injuries and infections. This technique utilizes polyvinylalcohol-foam and polyurethane drapes to create a vacuum, promoting granulation tissue formation and fluid evacuation.

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Area of Science:

Medical and Health Sciences
Surgical Innovation
Wound Healing Technologies

Background:

Traumatic soft tissue damage, including open and closed fractures, presents significant challenges in achieving secure and rapid wound healing.
Acute and chronic infections further complicate wound management, often requiring advanced therapeutic strategies.
Existing treatments may not always provide optimal conditions for tissue regeneration and infection control.

Purpose of the Study:

To introduce and evaluate vacuum sealing therapy as a novel concept for managing traumatic soft tissue damage and infections.
To assess the efficacy of vacuum sealing in promoting secure and rapid wound healing.
To investigate the impact of vacuum sealing on granulation tissue formation and fluid management in wounds.

Main Methods:

The vacuum sealing procedure involves filling the tissue defect with open-porous polyvinylalcohol-foam.
A semipermeable transparent Polyurethane drape is used to cover the entire wound surface.
A vacuum of 80 kPa is established using Redon-drainage tubes and vacuum bottles, ensuring complete fluid evacuation without compressing deeper tissues.

Main Results:

Vacuum sealing therapy demonstrated a significant benefit in the treatment of soft tissue defects.
The procedure led to the rapid formation of sound granulation tissue, a key indicator of healing.
Follow-up data from 121 patients undergoing the procedure between January 1992 and August 1993 supported its therapeutic advantages.

Conclusions:

Vacuum sealing therapy is an effective method for achieving secure and rapid wound healing in various traumatic conditions and infections.
The technique facilitates optimal wound bed preparation by evacuating fluids and promoting granulation.
This therapeutic approach represents a valuable advancement in the management of complex soft tissue wounds.