[Insulin allergy and insulin resistance (author's transl)]

The antigenicity of insulin is the cause of the side effects of insulin therapy such as insulin allergy, lipoatrophy at the site of injection and insulin resistance. Factors inherent in the individual patient are decisive for the antigenicity of insulin, as well as species specificity of the insulin,purity and galenical form. Clinical aspects and possibilities for treatment of insulin allergy, lipoatrophy and insulin resistance are discussed in relation to our own cases.