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Annotation of Plant Gene Function via Combined Genomics, Metabolomics and Informatics
Published on: June 17, 2012
GoMapMan: integration, consolidation and visualization of plant gene annotations within the MapMan ontology
Živa Ramsak1, Špela Baebler, Ana Rotter
1Department of Biotechnology and Systems Biology, National Institute of Biology, 1000 Ljubljana, Slovenia, Department of Knowledge Technologies, JoŽef Stefan Institute, 1000 Ljubljana, Slovenia, Department of Biology, Institute for Biology I, RWTH Aachen University, D-52056 Aachen, Germany and IBG-2: Plant Sciences, Institute for Bio- and Geosciences, Forschungszentrum Jülich, 52425 Jülich, Germany.
Abstract:
GoMapMan (http://www.gomapman.org) is an open web-accessible resource for gene functional annotations in the plant sciences. It was developed to facilitate improvement, consolidation and visualization of gene annotations across several plant species. GoMapMan is based on the MapMan ontology, organized in the form of a hierarchical tree of biological concepts, which describe gene functions. Currently, genes of the model species Arabidopsis and three crop species (potato, tomato and rice) are included. The main features of GoMapMan are (i) dynamic and interactive gene product annotation through various curation options; (ii) consolidation of gene annotations for different plant species through the integration of orthologue group information; (iii) traceability of gene ontology changes and annotations; (iv) integration of external knowledge about genes from different public resources; and (v) providing gathered information to high-throughput analysis tools via dynamically generated export files. All of the GoMapMan functionalities are openly available, with the restriction on the curation functions, which require prior registration to ensure traceability of the implemented changes.
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