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Related Experiment Video

Updated: May 6, 2026

Laryngeal Mask Airway LMA Placement in a Neonatal Patient Simulator Using a Non-Inflatable Supraglottic Airway SGA
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Non-pneumatic anti-shock garment (NASG), a first-aid device to decrease maternal mortality from obstetric hemorrhage:

Suellen Miller1, Eduardo F Bergel, Alison M El Ayadi

  • 1Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco, San Francisco, California, United States of America.

Plos One
|November 7, 2013
PubMed
Summary
This summary is machine-generated.

The Non-pneumatic Anti-Shock Garment (NASG) may reduce adverse outcomes in women with obstetric hemorrhage. Earlier NASG application showed faster shock recovery, suggesting potential benefits despite non-significant statistical results.

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Area of Science:

  • Obstetrics and Gynecology
  • Emergency Medicine
  • Public Health

Background:

  • Obstetric hemorrhage is a primary cause of maternal mortality globally.
  • The Non-pneumatic Anti-Shock Garment (NASG) is a potential intervention for hypovolemic shock.
  • Investigating early NASG application in primary health care settings is crucial.

Purpose of the Study:

  • To evaluate the effectiveness of the NASG applied before transport from primary health care centers (PHCs) to referral hospitals (RHs).
  • To determine if NASG reduces adverse outcomes in women with hypovolemic shock.
  • To assess the safety and secondary outcomes associated with NASG use.

Main Methods:

  • A cluster randomized trial involving 38 PHCs in Zambia and Zimbabwe.
  • Comparison of standard care versus standard care plus NASG prior to transport.
  • Primary outcomes included maternal mortality, severe morbidity, and a composite extreme adverse outcome (EAO).

Main Results:

  • The study enrolled 880 women, falling short of the planned sample size.
  • A non-significant 46% reduction in mortality odds and a 54% reduction in EAO were observed.
  • Women receiving the NASG demonstrated significantly faster recovery from shock (HR 1.25, p=0.03).

Conclusions:

  • Early NASG application may offer treatment benefits for women with hypovolemic shock, particularly when definitive care is delayed.
  • No significant adverse effects were noted, supporting NASG's safety as a temporizing measure.
  • Further pragmatic research with adequate sample size is recommended to confirm findings.