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Updated: May 6, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Elderly patients and intra-arterial stroke therapy
Thabele M Leslie-Mazwi1, Ronil V Chandra, Claus Z Simonsen
1Neuroendovascular, Neurologic Critical Care, Massachusetts General Hospital, Boston, USA.
Elderly patients over 80 experience more strokes. Intra-arterial stroke therapy (IAT) shows similar results to IV tPA but worse outcomes in the elderly.
Area of Science:
- Neurology
- Geriatrics
- Vascular Medicine
Background:
- Ischemic stroke incidence rises with age, especially over 80.
- Stroke treatment in the elderly is critical due to increasing rates.
- Early reperfusion is the only proven acute stroke therapy.
Purpose of the Study:
- To review intra-arterial stroke therapy (IAT) in elderly patients.
- To summarize studies on elderly patient response to IAT.
Main Methods:
- Review of existing literature on IAT in the elderly population.
- Analysis of studies comparing IAT outcomes in elderly versus younger stroke patients.
Main Results:
- Intra-arterial stroke therapy (IAT) has higher recanalization rates than IV tPA.
- Elderly patients may have worse outcomes after IAT despite similar recanalization and hemorrhage rates.
- Data on elderly response to IAT is limited.
Conclusions:
- Understanding IAT's efficacy and safety in the elderly is crucial.
- Further research is needed to optimize stroke treatment for older adults.
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