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Updated: May 6, 2026

Estimation of Telomeric Repeat-containing RNA from DNA/RNA Hybrid Complexes
Published on: December 5, 2025
Hybridization of mRNA and pre-mRNA with the sequences forming double-stranded structures in pre-mRNA
A P Ryskov1, S A Limborska, G P Georgiev
1Institute of Molecular Biology, Acad. of Sciences of the U.S.S.R., Moscow, Russia.
Abstract:
About 25% of the double-stranded sequences isolated from pre-mRNA are able to hybridize, after melting, with either mRNA or non-melted pre-mRNA. The retention of one branch of pre-mRNA hairpin in mRNA was suggested. It was also found that in addition to the hairpin-like structures comprising about 3% of the total sequences another 15% of the pre-mRNA sequences can form double-stranded structures upon annealing over a broad interval of Cot values.
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