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Type D personality predicts poor medication adherence in patients with heart failure in the USA
1School of Nursing, University of North Carolina at Chapel Hill, 435 Carrington Hall, CB# 7460, Chapel Hill, NC, 27599-7460, USA, jiarongw@email.unc.edu.
Insights
Type D personality was linked to poorer medication adherence in heart failure patients. Negative affectivity, a component of Type D personality, was specifically associated with medication adherence challenges.
Area of Science:
- Cardiology
- Psychology
- Behavioral Science
Background:
- Type D (distressed) personality is linked to adverse health outcomes and medication nonadherence.
- Previous research shows Type D personality is associated with poor medication adherence in coronary artery disease patients.
- The relationship between Type D personality and medication adherence in heart failure (HF) patients is not well understood.
Purpose of the Study:
- To investigate the association between Type D personality and medication adherence in patients diagnosed with heart failure.
- To determine if personality traits influence medication adherence in a heart failure population.
Main Methods:
- A sub-analysis of baseline data from a randomized controlled trial involving 84 US-based heart failure patients.
- Assessment of Type D personality using the Type D Personality Scale (DS14).
- Measurement of medication adherence using objective (Medication Event Monitoring System) and self-reported (Morisky Medication Adherence Scale) methods.
Main Results:
- Patients with Type D personality demonstrated a higher likelihood of poor medication adherence.
- Type D personality, when treated as a categorical variable, showed a significant association with medication adherence, even after adjusting for covariates.
- Negative affectivity, a facet of Type D personality, was found to be significantly associated with medication adherence.
Conclusions:
- Type D personality as a dimensional construct may not fully capture the personality components linked to poor health outcomes.
- Negative affectivity is a key component of Type D personality associated with medication adherence in heart failure patients.
- Interventions to improve medication adherence should consider patients with high negative affectivity, who are at increased risk for nonadherence and adverse health outcomes.
Background:
Type D (distressed) personality and medication nonadherence have been associated with poor health outcomes. Type D personality is associated with poor medication adherence in patients with coronary artery disease. However, the relationship between type D personality and medication adherence in patients with heart failure (HF) remains unknown.
Purpose:
Therefore, the goal of this study was to examine the association between type D personality and medication adherence in patients with HF.
Method:
This was a sub-analysis of baseline data from a randomized controlled trial with 84 patients with HF in the USA. Demographic, clinical, and psychological data were collected at baseline by interview, questionnaires, and medical record review. Type D personality was assessed using the Type D Personality Scale (DS14). Medication adherence was measured using both objective (Medication Event Monitoring System, MEMS) and self-reported (Morisky Medication Adherence Scale, MMAS-4) measures. Patients started medication adherence monitoring with the MEMS bottle at baseline and is used continuously for a month. Multiple regressions were used to explore the relationships between type D personality and medication adherence while adjusting for demographic, clinical, and psychological factors.
Results:
Patients with type D personality were more likely to have poor medication adherence. Type D personality was associated with medication adherence before and after adjusting for covariates when it was analyzed as a categorical variable. However, type D personality was not associated with medication adherence when analyzed as a dimensional construct. Negative affectivity, a component of type D personality, was associated with medication adherence.
Conclusion:
As a dimensional construct, type D personality may not reflect the components of the personality associated with poor outcomes. Negative affectivity was associated with medication adherence in patients with HF. Interventions aiming to improving/enhancing medication adherence need to take into account patients with the negative affectivity component of type D personality who are at higher risk for poor medication adherence, which may lead to adverse health outcomes.
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