Search research articles

Related Concept Videos

Pre-Procedural Guidelines for Assessing Blood Pressure

Pre-Procedural Guidelines for Assessing Blood Pressure

Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Neuroimmunology of Epilepsy: Mechanisms, Treatments, and Clinical Insights.

Epilepsy currents·2026

Same author

Closing the Gaps in Early Sepsis Fluid Resuscitation.

JAMA network open·2026

Same author

Minimal Fibrinolysis After Acute Intracerebral Hemorrhage Undercuts the Mechanism of Tranexamic Acid.

Journal of the American Heart Association·2026

Same author

Prophylactic Antiseizure Medication in Patients with Lobar Intracerebral Hemorrhage.

Neurocritical care·2025

Same author

Efficacy of andexanet alfa in non-surgical patients with spontaneous DOAC related intracerebral hemorrhage.

Clinical neurology and neurosurgery·2025

Same author

Biomarkers of Thromboelastography Platelet Mapping Predict Hematoma Expansion After Spontaneous Intracerebral Hemorrhage.

Stroke·2025

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: May 6, 2026

Study of Experimental Organ Donation Models for Lung Transplantation

Study of Experimental Organ Donation Models for Lung Transplantation

Published on: March 15, 2024

Practice variability in brain death determination: a call to action.

Claire N Shappell¹, Jeffrey I Frank, Khalil Husari

¹From the Pritzker School of Medicine (C.N.S., M.S.), University of Chicago; and Department of Neurology (J.I.F., K.H., F.G., A.A.), University of Chicago Medicine, IL.

|November 8, 2013

Summary

Brain death (BD) determination practices vary widely among hospitals, with many deviating from American Academy of Neurology (AAN) guidelines. Improved documentation and consistent policies are needed for accurate BD determination.

More Related Videos

Brain Death Induction in Mice Using Intra-Arterial Blood Pressure Monitoring and Ventilation via Tracheostomy

Brain Death Induction in Mice Using Intra-Arterial Blood Pressure Monitoring and Ventilation via Tracheostomy

Published on: April 17, 2020

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Published on: June 3, 2020

Related Experiment Videos

Last Updated: May 6, 2026

Study of Experimental Organ Donation Models for Lung Transplantation

Study of Experimental Organ Donation Models for Lung Transplantation

Published on: March 15, 2024

Brain Death Induction in Mice Using Intra-Arterial Blood Pressure Monitoring and Ventilation via Tracheostomy

Brain Death Induction in Mice Using Intra-Arterial Blood Pressure Monitoring and Ventilation via Tracheostomy

Published on: April 17, 2020

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Published on: June 3, 2020

Area of Science:

Neurology
Critical Care Medicine
Organ Donation

Background:

Brain death (BD) determination is critical for organ donation and patient management.
Adherence to established guidelines, such as those from the American Academy of Neurology (AAN), is essential for accurate diagnosis.
Variability in clinical practice can impact the reliability of BD determination.

Purpose of the Study:

To assess current practices in brain death determination.
To evaluate adherence to contemporary American Academy of Neurology (AAN) guidelines in a multi-hospital setting.
To identify areas of variability and non-compliance in BD determination protocols.

Main Methods:

Retrospective chart review of adult organ donors (≥16 years) from 68 Midwest hospitals in 2011.
Data collection focused on guideline adherence, preclinical testing, clinical examination, apnea testing, and ancillary tests.
Analysis of practice variations and overall compliance with AAN guidelines.

Main Results:

226 brain death organ donors were analyzed.
Significant deviations from AAN guidelines were observed in clinical examination and apnea testing.
Only 44.7% of cases strictly adhered to AAN guidelines, with 37.2% loosely adhering.
Complete documentation of brainstem areflexia was present in only 45.1% of cases.

Conclusions:

Wide variability exists in the documentation and practice of brain death determination.
This variability underscores the need for improved documentation standards and policy uniformity.
Targeted educational initiatives are recommended to ensure consistent application of contemporary BD determination guidelines.