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Related Experiment Video

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Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

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Thyroid Hemiagenesis Associated with Hashimoto's Thyroiditis.

D Nsame¹, A Chadli, L Hallab

¹Service d'Endocrinologie, Diabétologie et Maladies Métaboliques, Centre Hospitalier Universitaire Ibn Rochd 1, Quartier des Hôpitaux, Casablanca 20100, Morocco ; Résidante 3ème Endocrinologie, Maladie Métabolique et Nutrition, Centre Hospitalier Universitaire Ibn Rochd 1, Quartier des Hôpitaux, Casablanca 20100, Morocco.

Case Reports in Endocrinology

|November 8, 2013

Summary

Thyroid hemiagenesis, a rare congenital condition, involves the failure of one thyroid lobe to develop. This case highlights its association with Hashimoto

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Area of Science:

Endocrinology
Congenital Anomalies
Thyroid Disorders

Background:

Thyroid hemiagenesis is a rare congenital anomaly characterized by the incomplete development of one thyroid lobe.
This condition can present diagnostic challenges, particularly when associated with other thyroid pathologies.
Hashimoto's thyroiditis and Graves' hyperthyroidism are common autoimmune thyroid diseases that may coexist with hemiagenesis.

Purpose of the Study:

To report a unique case of thyroid hemiagenesis associated with Hashimoto's thyroiditis.
To illustrate the diagnostic process and management of this rare combined condition.
To discuss the potential evolution of thyroid disorders in the context of hemiagenesis.

Main Methods:

Clinical presentation and patient history review.
Diagnostic confirmation using thyroid scintiscanning to identify the absent lobe.
Ultrasonography and antithyroid antibody studies to confirm Hashimoto's thyroiditis.

Main Results:

A 23-year-old female presented with features initially suggestive of Graves' hyperthyroidism, later evolving into Hashimoto's thyroiditis.
Thyroid scintiscanning confirmed hemiagenesis of the right lobe and isthmus.
Treatment involved antithyroid drugs (thiamazole) followed by thyroid hormone substitution due to induced hypothyroidism.

Conclusions:

Thyroid hemiagenesis can be associated with autoimmune thyroid diseases like Hashimoto's thyroiditis.
Accurate diagnosis requires a combination of imaging and serological tests.
Management should be tailored to the specific thyroid dysfunction and associated anomalies.