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Updated: May 6, 2026
09:40
An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function
Published on: April 17, 2020
16.8K
Induction therapy for esophageal cancer
1Division of Thoracic Surgery, Department of Cardiothoracic Surgery, New York Presbyterian Hospital, Weill Cornell Medical College, New York, NY 10065, USA.
Thoracic Surgery Clinics
|November 9, 2013
Summary
Long-term survival for esophageal cancer is poor, even with surgery. Induction therapy before surgery may improve outcomes for locally advanced esophageal cancer.
Area of Science:
- Oncology
- Surgical Oncology
- Gastroenterology
Background:
- Esophageal cancer survival rates remain low (15-35%) despite treatment advances.
- Locoregionally advanced or metastatic disease at presentation contributes to poor long-term outcomes.
- Surgery alone offers limited locoregional control and survival (10-30%) for Stage III esophageal cancer patients.
Purpose of the Study:
- To examine the benefits of various induction therapy modalities for locally advanced esophageal cancer.
- To evaluate strategies aimed at improving long-term survival in esophageal cancer patients.
Main Methods:
- Review of current treatment modalities for locally advanced esophageal cancer.
- Analysis of induction therapy protocols combining surgery with chemotherapy and/or radiotherapy.
Main Results:
- Induction therapy aims to improve long-term survival rates in patients with locally advanced esophageal cancer.
- The article assesses the effectiveness of different induction therapy approaches.
Conclusions:
- Further research into induction therapy is crucial for improving esophageal cancer patient survival.
- Optimizing neoadjuvant treatment strategies is key to enhancing outcomes for locally advanced esophageal cancer.
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