Related Experiment Video
Updated: May 6, 2026

Author Spotlight: Investigating Wound Healing in Mice Models of Oronasal Fistulas
Published on: September 8, 2023
Does nasogastric feeding reduce distress after cleft palate repair in infants?
Julie Hughes1, Melanie Lindup, Sally Wright
1Great Ormond Street Hospital for Children, London.
Insights
Nasogastric (NG) feeding improved enteral intake post-cleft palate repair compared to oral feeding. Pain and morphine needs were similar between groups, but NG feeding reduced the need for IV fluids.
Area of Science:
- Pediatric Surgery
- Anesthesiology
- Nutritional Support
Background:
- Cleft palate repair is a common pediatric surgical procedure.
- Postoperative pain management and adequate nutrition are critical for recovery.
- Nasogastric (NG) feeding and oral feeding are potential methods for nutritional support after surgery.
Purpose of the Study:
- To compare the effectiveness of nasogastric (NG) feeding versus oral feeding on morphine requirements after primary cleft palate repair.
- To assess the secondary outcomes of enteral intake and fluid balance.
Main Methods:
- A pilot randomized controlled trial involving 50 infants (5-10 months) undergoing cleft palate repair.
- Infants were assigned to either NG or oral feeding post-surgery.
- Morphine consumption, painful episodes, and fluid/feed volumes were monitored in the first 24 hours.
Main Results:
- Morphine consumption and painful episodes were comparable between NG and oral feeding groups.
- Infants receiving NG feeding consumed significantly more feed volume (approximately three times) than the oral group.
- None of the NG-fed infants required intravenous fluids, compared to nine in the oral feeding group.
Conclusions:
- Nasogastric feeding is more effective for ensuring adequate enteral intake in the initial 24 hours after cleft palate repair.
- While pain and morphine requirements were similar, NG feeding reduced the need for intravenous fluid support.
- Further research is warranted to fully elucidate the benefits of NG feeding in this patient population.
Aims:
To determine the effect of nasogastric (NG) feeding compared with oral feeding on morphine requirements after primary cleft palate repair, and secondarily on enteral intake.
Methods:
This was a pilot study involving 50 infants, aged five to ten months, who were randomised to receive NG or oral feeding after palate repair. All infants received the same anaesthetic and analgesic management. Post-operatively, paracetamol and ibuprofen were administered regularly and intravenous (IV) morphine was given on demand using a nurse-controlled analgesia device. The primary outcome measure was the total morphine consumption in the first 24 hours. Secondary outcome measures included the numbers of painful episodes and the volumes of IV fluid and enteral feed administered.
Results:
Of the 50 infants enrolled, 18 and 23 received either NG or oral feeding, respectively, and completed the study. Numbers of painful episodes and morphine consumption in the first 24 hours were similar in each group. Volumes of feed administered in the first 24 hours were significantly different: the NG group received approximately three times more than the oral group. Nine of the oral group required IV fluids in the 24 hours compared with none in the NG group.
Conclusion:
NG feeding was more effective than oral feeding in the first 24 hours after surgery, but numbers of painful episodes recorded were similar. Further research is required.
Related Concept Videos
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Enteral Nutrition I: Orogastric and Nasogastric Feeding
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Suctioning the Nasopharyngeal Airway
Equipment Required
Administering Oxygen by Nasal Cannula
Nasal Cannulas
A nasal cannula is a lightweight tube split into two prongs placed in the nostrils,...
Peptic Ulcer Disease V: Surgical Management and Nursing Care
Surgical Interventions for Peptic Ulcer Disease
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...